Therapeutic Modulation of Gut Microbiota in Functional Bowel Disorders

• Published in: Journal of neurogastroenterology and motility Vol. 23; no. 1; pp. 9 - 19
• Main Authors: Lee, Hyo Jeong, Choi, Jong Kyoung, Ryu, Han Seung, Choi, Chang Hwan, Kang, Eun Hee, Park, Kyung Sik, Min, Yang Won, Hong, Kyoung Sup
• Format: Journal Article
• Language: English
• Published: Korea (South) Korean Society of Neurogastroenterology and Motility 01.01.2017; 대한소화기 기능성질환∙운동학회
• Subjects: Review; 내과학; Probiotics; Microbiota; Diet; Fecal microbiota transplantation; Irritable bowel syndrome
• ISSN: 2093-0879; 2093-0887
• DOI: 10.5056/jnm16124

Functional bowel disorders (FBDs) are functional gastrointestinal disorders with symptoms attributable to the middle or lower gastrointestinal tract. These include irritable bowel syndrome, functional bloating, functional constipation, functional diarrhea, and unspecified FBD. Increasing evidence has emerged of late that intestinal microbiota is involved in the pathogenesis of FBDs. In this review, the therapeutic benefits and future perspectives of the currently available strategies for modifying the gut microbiota in FBDs are described, focusing primarily on irritable bowel syndrome and functional constipation.