Synthesis of β-alkoxy- N -protected phenethylamines via one-pot copper-catalyzed aziridination and ring opening
A regioselective, copper-catalyzed, one-pot aminoalkoxylation of styrenes using primary and secondary alcohols and three different iminoiodanes as alkoxy and nitrogen sources respectively, is reported. The β-alkoxy- -protected phenethylamines obtained were used to synthesise β-alkoxy- -benzylpheneth...
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Published in | RSC advances Vol. 8; no. 49; pp. 27919 - 27923 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
England
Royal Society of Chemistry
01.01.2018
The Royal Society of Chemistry |
Subjects | |
Online Access | Get full text |
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Summary: | A regioselective, copper-catalyzed, one-pot aminoalkoxylation of styrenes using primary and secondary alcohols and three different iminoiodanes as alkoxy and nitrogen sources respectively, is reported. The β-alkoxy-
-protected phenethylamines obtained were used to synthesise β-alkoxy-
-benzylphenethylamines which are interesting new compounds that could act as possible neuronal ligands. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2046-2069 2046-2069 |
DOI: | 10.1039/c8ra03815e |