Soyamilk fermented with riboflavin-producing Lactobacillus plantarum CRL 2130 reverts and prevents ariboflavinosis in murine models

• Published in: British journal of nutrition Vol. 116; no. 7; pp. 1229 - 1235
• Main Authors: Juarez del Valle, M., Laiño, J. E., de Moreno de LeBlanc, A., Savoy de Giori, G., LeBlanc, J. G.
• Format: Journal Article
• Language: English
• Published: Cambridge, UK Cambridge University Press 14.10.2016
• Subjects: Animal models; Animals; Diet; Female; Fermentation; Human and Clinical Nutrition; Lactobacillus plantarum; Lactobacillus plantarum - metabolism; Mice; Mice, Inbred BALB C; Milk; Prevention; Riboflavin - administration & dosage; Riboflavin - biosynthesis; Riboflavin Deficiency - etiology; Riboflavin Deficiency - prevention & control; Soy Milk - chemistry; Soy Milk - metabolism; Soy products; Vitamin B; Riboflavin; Vitamin deficiency; Lactic acid bacteria; Bio-enriched foods; Soyamilk; LAB lactic acid bacteria; RDD riboflavin-deficient diet; CD control diet; DR depleted–repleted; EGRAC erythrocyte glutathione reductase activation coefficient
• ISSN: 0007-1145; 1475-2662
• DOI: 10.1017/S0007114516003378

It has been previously shown that Lactobacillus plantarum CRL 2130 is able to produce riboflavin in soyamilk. The aim of the present study was to evaluate the efficiency of this riboflavin-bio-enriched soyamilk to revert and/or prevent the nutritional deficiency of riboflavin using different animal models. When used to supplement the diets of previously depleted animals, it was shown that the growth, riboflavin status and morphology of the small intestines reverted to normal parameters and were similar to animals supplemented with commercial riboflavin. In the prevention model, the same tendency was observed, where animals that received soyamilk fermented with L. plantarum CRL 2130 did not show signs of riboflavin deficiency. This new bio-fortified soya-based product could be used as part of normal diets to provide a more natural alternative to mandatory fortification with riboflavin for the prevention of its deficiency.