Is thyroid dysfunction a common cause of telogen effluvium?: A retrospective study

• Published in: Medicine (Baltimore) Vol. 103; no. 1; p. e36803
• Main Authors: Bin Dayel, Salman, Hussein, Ramadan S, Atia, Tarek, Abahussein, Othman, Al Yahya, Rand S, Elsayed, Shereen H
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 05.01.2024
• Subjects: Observational Study
• ISSN: 0025-7974; 1536-5964
• DOI: 10.1097/MD.0000000000036803

Telogen effluvium (TE) is a common cause of hair loss characterized by excessive resting hair shedding. Thyroid dysfunction is one of the possible causes of TE. On the other hand, the link between thyroid disorder and TE is still being debated. The aim of this retrospective is to investigate the link between thyroid dysfunction and TE. This retrospective study included 500 female patients with TE who had thyroid function testing between January 2012 and December 2022. Patients were eligible if they had a confirmed TE diagnosis and thyroid function tests within 3 months of being diagnosed with TE. The thyroid function of the participants was classified as euthyroid, hypothyroidism, or hyperthyroidism. The severity of hair loss was determined using the severity of alopecia tool (SALT) score. The study included 500 TE females, 248 of whom were euthyroid, 150 had hypothyroidism, and 102 had hyperthyroidism. The hypothyroid group had a significantly higher mean SALT score than the other 2 groups. Furthermore, patients in the hypothyroid group had a higher proportion of severe hair loss. The mean SALT score did not differ significantly between groups with normal thyroid function and those with hyperthyroidism. A common cause of TE is thyroid dysfunction, particularly hypothyroidism. Patients with hypothyroidism have more severe hair loss than those with normal thyroid function or hyperthyroidism. To effectively identify and manage such cases, thyroid function testing should be included in the diagnostic workup of patients with TE.