Thymoquinone in the clinical treatment of cancer: Fact or fiction?

Thymoquinone (TQ) is the bioactive phytochemical constituent of the seeds oil of Nigella sativa. In vitro and in vivo research has thoroughly investigated the anticancer effects of TQ against several cancer cell lines and animal models. As a result, a considerable amount of information has been gene...

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Bibliographic Details
Published inPharmacognosy reviews Vol. 7; no. 14; pp. 117 - 120
Main Author Abukhader, Majed M
Format Journal Article
LanguageEnglish
Published India Medknow Publications and Media Pvt. Ltd 01.07.2013
Phcog.net
Medknow Publications & Media Pvt Ltd
Subjects
Antimitotic agents
Antineoplastic agents
Apoptosis
Bioavailability
Breast cancer
Cancer
Cancer therapies
Care and treatment
Cell cycle
Cell growth
Chemical properties
Disease
Medical research
Nanoparticles
Nigella sativa
Proteins
Quinone
Review
Studies
Testing
Vegetable oils
thymoquinone
pharmacokinetics
Breast cancer
drug delivery
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Summary:Thymoquinone (TQ) is the bioactive phytochemical constituent of the seeds oil of Nigella sativa. In vitro and in vivo research has thoroughly investigated the anticancer effects of TQ against several cancer cell lines and animal models. As a result, a considerable amount of information has been generated from research thus providing a better understanding of the anti-proliferating activity of this compound. Therefore, it is appropriate that TQ should move from testing on the bench to clinical experiments. The purpose of this review is to highlight the potential of TQ as an anticancer agent and the chances of this compound in the clinical treatment of cancer, with special attention on breast cancer treatment.
ISSN:0973-7847
0976-2787
DOI:10.4103/0973-7847.120509