Surface Atrial Frequency Analysis in Patients with Atrial Fibrillation: Assessing the Effects of Linear Left Atrial Ablation
Introduction: Our group has shown previously that measurements of atrial frequency can be obtained from surface 12‐lead ECG recordings of patients during atrial fibrillation (AF), using a combination of principal component and Fourier transform algorithms. Such measurements are reproducible over tim...
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Published in | Journal of cardiovascular electrophysiology Vol. 16; no. 8; pp. 838 - 844 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
350 Main Street , Malden , MA 02148-5018 , USA , and 9600 Garsington Road , Oxford OX4 2DQ , UK
Blackwell Science Inc
01.08.2005
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Subjects | |
Online Access | Get full text |
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Summary: | Introduction: Our group has shown previously that measurements of atrial frequency can be obtained from surface 12‐lead ECG recordings of patients during atrial fibrillation (AF), using a combination of principal component and Fourier transform algorithms. Such measurements are reproducible over time and change with drug manipulation of the arrhythmia.
Aims: To determine whether linear left atrial ablation, using a combination of “roof” and “mitral isthmus” lines results in changes in surface atrial frequency during AF and to assess the contribution of each individual line when sited sequentially.
Methods and Results: Computerized recordings from 26 patients, who had undergone linear ablation procedures for AF, were reviewed. The atrial signal was extracted from the 12‐lead ECG data by principal component analysis and the main frequency component identified using Fourier analysis. Atrial frequency before and after these two standard ablation lines was compared. Atrial frequency decreased significantly after the combination of roof and mitral isthmus lines (5.66 vs 5.15 Hz) and when either roof (5.61 vs 5.13 Hz) or mitral isthmus (5.89 vs 5.75 Hz) lines were sited first. However, only the roof line led to a significant reduction in atrial frequency when sited second (5.64 vs 5.49 Hz).
Conclusions: Measurements of atrial frequency can be obtained from surface 12‐lead ECG recordings during AF and change as predicted in response to linear left atrial ablation. This technique may be useful in assessing antiarrhythmic treatments for AF. |
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Bibliography: | istex:4F444E22ABC8A6CFB533DCCD764E349B676A88A0 ark:/67375/WNG-9RTR3Z97-B ArticleID:JCE40456 Manuscript received 16 June 2004; Revised manuscript received 8 December 2004; Accepted for publication 25 January 2005. Dr. Philip Langley is supported by a research grant from EPSRC. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1045-3873 1540-8167 |
DOI: | 10.1111/j.1540-8167.2005.40456.x |