Completely converting a blood service region to the use of safer plasma

• Published in: Transfusion (Philadelphia, Pa.) Vol. 40; no. 10; pp. 1264 - 1267
• Main Authors: McCarthy, Leo J., Danielson, Constance F.M., Rothenberger, Sandra S., Parker, Carol, Weidner, John, Miraglia, Charles, Matus, Deborah, Waxman, Dan
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Science Inc 01.10.2000; Blackwell Publishing
• Subjects: Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Blood Banks - organization & administration; Blood Donors; Blood Transfusion - standards; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis; CIRBC = Central Indiana Regional Blood Center; Consumer Product Safety - standards; CPP = cryopoor FFP; Detergents - pharmacology; DR = donor retested; Humans; Indiana; MAC = Medical Advisory Committee; Medical sciences; Plasma - drug effects; S/D = solvent/detergent; SDP = solvent/detergent‐treated plasma; TAC = Technical Advisory Committee; TNBP = tri(N‐butyl)phosphate; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; Indiana; Performance evaluation; Human; Detergent; Transfusion; Chemical treatment; Regional center; Health service; Solvent; Transfusion safety; Blood plasma
• ISSN: 0041-1132; 1537-2995
• DOI: 10.1046/j.1537-2995.2000.40101264.x

BACKGROUND: Three types of plasma are widely available for transfusion. Two plasma components, FFP donor retested (FFP‐DR), and solvent/detergent‐treated plasma (SDP), are now considered to be safer from infectious complications than FFP. STUDY DESIGN AND METHODS: A large regional blood center attempted to provide FFP‐DR exclusively to all its 42 hospitals. Significant planning, increases in computer capabilities, and expansion of component storage areas were completed before initiation of this program. RESULTS: During the first 6 months of the FFP‐DR program, the blood center was not able to supply the entire region exclusively with FFP‐DR. Consequently, SDP was utilized to supplement the program and to successfully and completely convert the region's 42 hospitals to the use of safer plasma. CONCLUSION: Two new plasma components were utilized to completely convert a blood service region to the use of safer plasma.