Neutral Tridentate PNP Ligands and Their Hybrid Analogues: Versatile Non-Innocent Scaffolds for Homogeneous Catalysis

• Published in: Angewandte Chemie (International ed.) Vol. 48; no. 47; pp. 8832 - 8846
• Main Authors: van der Vlugt, Jarl Ivar, Reek, Joost N.H
• Format: Journal Article
• Language: English
• Published: Weinheim Wiley-VCH Verlag 09.11.2009; WILEY-VCH Verlag; WILEY‐VCH Verlag
• Subjects: Catalysis; cooperative catalysis; CH activation; homogeneous catalysis; Ligands; Metals - chemistry; N,P ligands; Phosphines - chemistry; Phosphorus - chemistry; Pyridines - chemical synthesis; Pyridines - chemistry; P ligands; Ruthenium - chemistry; tridentate ligands
• ISSN: 1433-7851; 1521-3773
• DOI: 10.1002/anie.200903193

Ligands in coordination chemistry and homogeneous catalysis are traditionally "static" spectators that do not actively participate in the catalytic cycle. However, such classic systems do not provide additional "handles" that could facilitate or trigger alternative productive reaction pathways. Recent advances in the use of novel nitrogen-centered pincer systems have unveiled interesting opportunities for cooperative catalysis. The chemistry of pyridine-derived, neutral ligands is discussed, with a specific focus on their non-innocent behavior and potential as facilitators for metal-mediated organic transformations. This overview should provide inspiration and an incentive to incorporate non-innocent ligands and their metal complexes within old and new homogeneously catalyzed reactions.