Health Benefits of Exercise

Overwhelming evidence exists that lifelong exercise is associated with a longer health span, delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is the molecular mechanisms by which exercise sustains and improves quality of life. The current review begins with two s...

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Bibliographic Details
Published inCold Spring Harbor perspectives in medicine Vol. 8; no. 7; p. a029694
Main Authors Ruegsegger, Gregory N., Booth, Frank W.
Format Journal Article
LanguageEnglish
Published United States Cold Spring Harbor Laboratory Press 01.07.2018
Subjects
Cardiorespiratory Fitness - physiology
Diabetes Mellitus, Type 2 - prevention & control
Exercise - physiology
Exercise - psychology
Healthy Lifestyle - physiology
Humans
Mental Health
Mitochondria - physiology
Multifactorial Inheritance - genetics
Prognosis
Quality of Life
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Summary:Overwhelming evidence exists that lifelong exercise is associated with a longer health span, delaying the onset of 40 chronic conditions/diseases. What is beginning to be learned is the molecular mechanisms by which exercise sustains and improves quality of life. The current review begins with two short considerations. The first short presentation concerns the effects of endurance exercise training on cardiovascular fitness, and how it relates to improved health outcomes. The second short section contemplates emerging molecular connections from endurance training to mental health. Finally, approximately half of the remaining review concentrates on the relationships between type 2 diabetes, mitochondria, and endurance training. It is now clear that physical training is complex biology, invoking polygenic interactions within cells, tissues/organs, systems, with remarkable cross talk occurring among the former list.
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SourceType-Scholarly Journals-1
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ISSN:2157-1422
2472-5412
DOI:10.1101/cshperspect.a029694