Rapid, sequential bilateral acute carotid blowout syndrome

• Published in: Neuroradiology Vol. 55; no. 4; pp. 475 - 481
• Main Authors: Liu, Hon-Man, Yang, Chung-Yi, Lee, Chung-Wei, Wang, Yao-Hung, Chen, Ya-Fang
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer-Verlag 01.03.2013; Springer Nature B.V
• Subjects: Acute Disease; Adult; Aged; Carotid Artery Diseases - diagnostic imaging; Carotid Artery Diseases - etiology; Carotid Artery Diseases - surgery; Clinical outcomes; Fatal Outcome; Head & neck cancer; Head and Neck Neoplasms - complications; Head and Neck Neoplasms - diagnostic imaging; Head and Neck Neoplasms - surgery; Head and Neck Radiology; Humans; Imaging; Male; Medical treatment; Medicine; Medicine & Public Health; Middle Aged; Neurology; Neuroradiology; Neurosciences; Neurosurgery; Postoperative Complications - diagnostic imaging; Postoperative Complications - surgery; Radiation therapy; Radiography; Radiology; Risk factors; Treatment Outcome; Veins & arteries; Occlusion; Carotid artery; Radiotherapy; Blowout; Outcome
• ISSN: 0028-3940; 1432-1920
• DOI: 10.1007/s00234-013-1151-z

Introduction This study aims to report the treatment and outcome of sequential bilateral acute carotid artery blowout syndrome. Methods From 2004 to 2010, we treated seven male patients with sequential bilateral blowout syndrome long after irradiation treatment for head and neck cancer. After first common carotid artery (CCA)-internal carotid artery (ICA) rupture, six were treated with CCA-ICA occlusion and one with graft stenting. The contralateral ICAs were normal or stenotic on angiography in all patients. After the contralateral CCA-ICA rupture, five patients received CCA-ICA occlusion, one received graft stent treatment, and one received no treatment. Results Five of the seven patients died soon after the final treatment. Two patients developed cerebral infarctions (one treated with bilateral stenting, one treated with occlusion), one died from extensive local infection, one died soon after a third treatment, one died of progression of the disease, and one refused a second treatment and died soon after the diagnostic angiography. Two patients survived with follow-up periods of 1 and 5 years. In all seven patients, the contralateral CCA-ICA blowout occurred within 3 months after the first ICA occlusion. Conclusion Bilateral ICA occlusion is an alternative management for sequential carotid artery blowout, but the mortality is high and outcome is poor. A normal angiogram cannot exclude the possibility of rapid development of a contralateral carotid artery blowout shortly after a first episode in patients who have received radiotherapy for head and neck cancer.