The enhancin gene: One of the genetic determinants of population variation in baculoviral virulence

It was established that the virulence of the North American baculovirus strain LdMNPV-45 is almost two orders of magnitude higher than the virulence of the Asian strain LdMNPV-27 and does not depend on the test host population (gypsy moth). The Asian strain carries deletions in bro-p and vef-1 genes...

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Published inDoklady. Biochemistry and biophysics Vol. 465; no. 1; pp. 351 - 353
Main Authors Martemyanov, V. V., Kabilov, M. R., Tupikin, A. E., Baturina, O. A., Belousova, I. A., Podgwaite, J. D., Ilynykh, A. V., Vlassov, V. V.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.11.2015
Springer Nature B.V
Subjects
Animals
Baculoviridae - genetics
Baculoviridae - isolation & purification
Baculoviridae - pathogenicity
Baculovirus
Biochemistry
Biological and Medical Physics
Biomedical and Life Sciences
Biophysics
Biophysics and Molecular Biology
Genetic Variation
Genomics
Life Sciences
Moths - virology
Polymorphism
Viral Proteins - genetics
Virology
Virulence - genetics
Viruses
DOKLADY Biochemistry
American Strain
Gypsy Moth
Asian Strain
Bacu
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Summary:It was established that the virulence of the North American baculovirus strain LdMNPV-45 is almost two orders of magnitude higher than the virulence of the Asian strain LdMNPV-27 and does not depend on the test host population (gypsy moth). The Asian strain carries deletions in bro-p and vef-1 genes (82 and 91%, respectively). In accordance with the published data, the product of the latter can greatly increase the virulence of the virus. This result indicates that the population polymorphism of the virulence of baculoviruses can be explained by the vef-1 gene deletion.
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ISSN:1607-6729
1608-3091
DOI:10.1134/S1607672915060022