Usefulness of serum CA 15.3 and histopathological prognostic indices in breast cancer

Prognostic factors influence the modality and course of therapy in breast cancer. These include both histopathological and biochemical variables. This study was aimed to find out if any correlation exists between the biochemical tumor marker-serum CA 15.3, and the lymph node staging of Nottingham�...

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Bibliographic Details
Published inIndian journal of clinical biochemistry Vol. 20; no. 1; pp. 165 - 168
Main Authors Nalini, R, Wilma Delphine Silvia, C R, Makhija, Purnima M, Uthappa, Sheila
Format Journal Article
LanguageEnglish
Published India Springer Nature B.V 01.01.2005
Springer India
Subjects
Breast cancer
Nottingham’s Prognostic Index
Breast Cancer
CA 15.3
NPI
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Summary:Prognostic factors influence the modality and course of therapy in breast cancer. These include both histopathological and biochemical variables. This study was aimed to find out if any correlation exists between the biochemical tumor marker-serum CA 15.3, and the lymph node staging of Nottingham's Prognostic Index (NPI). It was observed that serum CA 15.3 showed a statistically significant correlation with lymph node staging of NPI. Therefore it is concluded that CA 15.3 can be utilized as a useful prognostic marker, particularly in cases where histopathological variables such as tumor size and grade have been altered by pre-operative chemotherapy.
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ISSN:0970-1915
0974-0422
DOI:10.1007/BF02893065