KAREBrowser: SNP database of Korea Association REsource Project

• Published in: BMB reports Vol. 45; no. 1; pp. 47 - 50
• Main Authors: Hong, C.B., National Institute of Health, Cheongwon, Republic of Korea, Kim, Y.J., National Institute of Health, Cheongwon, Republic of Korea, Moon, S.H., National Institute of Health, Cheongwon, Republic of Korea, Shin, Y.A., National Institute of Health, Cheongwon, Republic of Korea, Cho, Y.S., National Institute of Health, Cheongwon, Republic of Korea, Lee, J.Y., National Institute of Health, Cheongwon, Republic of Korea
• Format: Journal Article
• Language: English
• Published: Korea (South) 생화학분자생물학회 01.01.2012
• Subjects: Adult; Aged; BANQUE DE DONNEES; BASES DE DATOS; Databases, Genetic; Genome; Genome-Wide Association Study; Genotype; GWAS; Human genome; Humans; Internet; Korea; Middle Aged; Polymorphism, Single Nucleotide - genetics; SNP; 화학; Korea
• ISSN: 1976-6696; 1976-670X
• DOI: 10.5483/BMBRep.2012.45.1.47

The International HapMap Project and the Human Genome Diversity Project (HGDP) provide plentiful resources on human genome information to the public. However, this kind of information is limited because of the small sample size in both databases. A Genome-Wide Association Study has been conducted with 8,842 Korean subjects as a part of the Korea Association Resource (KARE) project. In an effort to build a publicly available browsing system for genome data resulted from large scale KARE GWAS, we developed the KARE browser. This browser provides users with a large amount of single nucleotide polymorphisms (SNPs) information comprising 1.5 million SNPs from population-based cohorts of 8,842 samples. KAREBrowser was based on the generic genome browser (GBrowse), a web-based application tool developed for users to navigate and visualize the genomic features and annotations in an interactive manner. All SNP information and related functions are available at the web site http://ksnp.cdc.go.kr/karebrowser/.