Comparison of Skin Substitutes for Acute and Chronic Wound Management

Abstract Chronic and acute wounds, such as diabetic foot ulcers and burns, respectively, can be difficult to treat, especially when autologous skin transplantations are unavailable. Skin substitutes can be used as a treatment alternative by providing the structural elements and growth factors necess...

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Bibliographic Details
Published inSeminars in plastic surgery Vol. 35; no. 3; pp. 171 - 180
Main Authors Bay, Caroline, Chizmar, Zachary, Reece, Edward M., Yu, Jessie Z., Winocour, Julian, Vorstenbosch, Joshua, Winocour, Sebastian
Format Journal Article
LanguageEnglish
Published 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA Thieme Medical Publishers, Inc 01.08.2021
SeriesHealing, Inflammation, and Fibrosis
Subjects
Review
Review Article
chronic wound treatment
epidermal replacement
skin substitutes
acute wound treatment
dermal replacement
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Summary:Abstract Chronic and acute wounds, such as diabetic foot ulcers and burns, respectively, can be difficult to treat, especially when autologous skin transplantations are unavailable. Skin substitutes can be used as a treatment alternative by providing the structural elements and growth factors necessary for reepithelialization and revascularization from a nonautologous source. As of 2020, there are 76 commercially available skin substitute products; this article provides a review of the relevant literature related to the major categories of skin substitutes available.
Bibliography:ObjectType-Article-2
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ISSN:1535-2188
1536-0067
DOI:10.1055/s-0041-1731463