Aortic Valvular Regurgitation: Prevalence and Clinical Characteristics in a Predominantly Obese Adult Population Not Taking Anorexigens
Background: We recently reported the prevalence of aortic regurgitation (AR) by Doppler echocardiography (echo) in obese subjects to be higher than in some previous reports. Objective: To describe the prevalence of AR in an obese population not taking anorexigens as a function of demographic charact...
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Published in | Echocardiography (Mount Kisco, N.Y.) Vol. 23; no. 7; pp. 569 - 576 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Malden, USA
Blackwell Publishing Inc
01.08.2006
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Subjects | |
Online Access | Get full text |
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Summary: | Background: We recently reported the prevalence of aortic regurgitation (AR) by Doppler echocardiography (echo) in obese subjects to be higher than in some previous reports. Objective: To describe the prevalence of AR in an obese population not taking anorexigens as a function of demographic characteristics, cardiovascular risk factors, and other potential predictors. Methods: In 539 adult subjects, cardiovascular status was evaluated by medical history, physical examination, and Doppler echocardiograms performed according to a standardized imaging protocol. Echocardiographic readers were blinded as to each subject's medical and medication histories. Associations of AR with demographic and comorbid factors were examined. Results: Subjects had a mean (± SD) body mass index (BMI) of 35 ± 7 kg/m2, and were predominantly white (87.6%), females (74%), with a mean age of 47 ± 12 years. AR by Food and Drug Administration criteria (≥mild) was present in 4.1% of the subjects. Covariates significantly associated with AR were increasing age (P < 0.001), presence of a history of hypertension (P = 0.001), left ventricular (LV) internal dimensions (P < 0.005), and tricuspid and mitral regurgitation grade (P < 0.001). Conclusions: Clinical and Doppler echo evaluation of a large, predominantly obese, adult population revealed that AR was more prevalent than in some previous reports and was highly correlated with increased age, presence of a history of hypertension, LV internal dimensions, tricuspid and mitral regurgitation. |
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Bibliography: | istex:EC93C6973D5F211C0A4435BD8BB179BD78FAECCC ArticleID:ECHO278 ark:/67375/WNG-4GK042NC-5 This work was presented at the 10th Annual Scientific Sessions of the American Society of Echocardiography, Washington DC, June 13–15, 1999. ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0742-2822 1540-8175 |
DOI: | 10.1111/j.1540-8175.2006.00278.x |