Unexplained lymphadenopathy in sickle cell disease

Progressive lymphadenopathy in a previously healthy female adult with homozygous sickle cell disease (SCD) was found to be due to infection with the human immunodeficiency virus (HIV). Detailed questioning identified several risk factors for HIV in this apparently low-risk patient. Parenteral therap...

Full description

Saved in:
Bibliographic Details
Published inEuropean journal of haematology Vol. 40; no. 2; p. 155
Main Authors Keidan, A J, Hamon, M D, Franklin, I M, Mawson, S
Format Journal Article
LanguageEnglish
Published England 01.02.1988
Subjects
Adult
AIDS-Related Complex - complications
Anemia, Sickle Cell - complications
Female
HIV Seropositivity - complications
Homozygote
Humans
Sickle Cell Trait - complications
Sickle Cell Trait - genetics
Online AccessGet more information

Cover

More Information
Summary:Progressive lymphadenopathy in a previously healthy female adult with homozygous sickle cell disease (SCD) was found to be due to infection with the human immunodeficiency virus (HIV). Detailed questioning identified several risk factors for HIV in this apparently low-risk patient. Parenteral therapy and heterosexual relationships while abroad may place such SCD patients at risk of HIV infection and its sequelae. The additional risk due to the underlying immunological abnormalities which have been identified in SCD patients is unclear in the absence of prospective studies or reported cases.
ISSN:0902-4441
DOI:10.1111/j.1600-0609.1988.tb00813.x