Chronic Obstructive Pulmonary Disease and Hepatitis C

Chronic obstructive pulmonary disease (COPD) is a preventable, treatable disease with significant extrapulmonary manifestations that could affect negatively its course in some patients. Hepatitis C virus infection (HCV), on the other hand, is associated with a number of extrahepatic manifestations....

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Bibliographic Details
Published inFolia Medica Vol. 59; no. 2; pp. 132 - 138
Main Authors Mekov, Evgeni V, Petkov, Rosen E, Kostadinov, Dimitar T, Antonov, Krasimir A, Jelev, Deian T
Format Journal Article
LanguageEnglish
Published Bulgaria MEDICAL UNIVERSITY- PLOVDIV 01.06.2017
Pensoft Publishers
Subjects
Age Distribution
Asthma
Blood & organ donations
Chronic obstructive pulmonary disease
Comorbidity
COPD
Disease Progression
Epidemiology
Female
Gene expression
HCV
Hepatitis
Hepatitis C
Hepatitis C, Chronic - diagnosis
Hepatitis C, Chronic - epidemiology
Hepatitis C, Chronic - therapy
HIV
Human immunodeficiency virus
Humans
Infections
Interferon
Liver
Liver cirrhosis
Lymphoma
Male
Prevalence
Prognosis
Pulmonary arteries
Pulmonary Disease, Chronic Obstructive - diagnosis
Pulmonary Disease, Chronic Obstructive - epidemiology
Pulmonary Disease, Chronic Obstructive - therapy
Pulmonary hypertension
Risk Assessment
Severity of Illness Index
Sex Distribution
Viral infections
HCV
comorbidity
hepatitis C
COPD
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Summary:Chronic obstructive pulmonary disease (COPD) is a preventable, treatable disease with significant extrapulmonary manifestations that could affect negatively its course in some patients. Hepatitis C virus infection (HCV), on the other hand, is associated with a number of extrahepatic manifestations. COPD patients have increased prevalence of HCV and patients with HCV, especially older ones, have increased prevalence and faster progression of COPD. HCV infection exerts long-term effects on lung tissue and is an additional risk factor for the development of COPD. The presence of HCV is associated with an accelerated loss of lung function in COPD patients, especially in current smokers. COPD could represent extrahepatic manifestation associated with HCV infection. The aim of this article was to review the literature on prevalence of HCV in COPD and vice versa, pathogenetic link and the consequences of their mutual existence.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:0204-8043
1314-2143
DOI:10.1515/folmed-2017-0018