Necrotizing sialometaplasia in a patient who is HIV positive: a case report

• Published in: Special care in dentistry Vol. 30; no. 4; p. 160
• Main Authors: Silva, Alessandra Dutra, Silva, Carolina Amália Barcellos, Furuse, Cristiane, Nunes e Souza, Rodrigo Calado, da Costa, Mauro Henrique Melo, de Araújo, Vera Cavalcanti
• Format: Journal Article
• Language: English
• Published: United States 01.07.2010
• Subjects: Carcinoma, Squamous Cell - diagnosis; Diagnosis, Differential; HIV Seropositivity - complications; Humans; Male; Middle Aged; Mouth Neoplasms - diagnosis; Oral Ulcer - diagnosis; Palate, Hard - pathology; Salivary Glands, Minor - pathology; Sialometaplasia, Necrotizing - diagnosis
• ISSN: 1754-4505
• DOI: 10.1111/j.1754-4505.2010.00142.x

Necrotizing sialometaplasia (NS) is a self-limiting, benign, inflammatory disease of the minor salivary glands of the hard palate. The main significance of the NS lesion lies in the fact that it may be mistaken for mucoepidermoid or squamous cell carcinoma. A case report is presented of a patient with NS who was HIV positive; the lesion was located in the minor salivary glands of the hard palate. Clinically, the lesion presented as a deep ulcer with slightly elevated irregular borders and a necrotic base in the hard palate. Histologically, the tissue was characterized by squamous metaplasia of ducts and acini, lobular coagulation necrosis, and pseudoepitheliomatous hyperplasia of the overlying epithelium. The lesion disappeared completely after 2 weeks.