The physiology and emerging roles of antidiuretic hormone

The antidiuretic hormone (ADH) vasopressin is a simple peptide hormone with a number of complex, essential physiological actions. It is becoming clear that this hormone is developing an important therapeutic role in a number of different conditions. These include vasodilatory shock due to sepsis or...

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Bibliographic Details
Published inInternational journal of clinical practice (Esher) Vol. 56; no. 10; p. 777
Main Author Singh Ranger, G
Format Journal Article
LanguageEnglish
Published England 01.12.2002
Subjects
Heart Arrest - drug therapy
Hemorrhage - drug therapy
Hemostatics - pharmacology
Hemostatics - therapeutic use
Humans
Renal Agents - pharmacology
Renal Agents - therapeutic use
Shock - drug therapy
Thoracic Surgery - methods
Vasoconstrictor Agents - pharmacology
Vasoconstrictor Agents - therapeutic use
Vasopressins - physiology
Vasopressins - therapeutic use
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Summary:The antidiuretic hormone (ADH) vasopressin is a simple peptide hormone with a number of complex, essential physiological actions. It is becoming clear that this hormone is developing an important therapeutic role in a number of different conditions. These include vasodilatory shock due to sepsis or cardiac surgery, cardiac arrest, and prolonged/excessive bleeding caused by, for example, variceal haemorrhage. This article reviews the physiology of ADH relevant to these actions and scrutinises the evidence for its therapeutic applications.
ISSN:1368-5031
DOI:10.1111/j.1742-1241.2002.tb11375.x