Enhanced Fe Ion-Uptake Activity in Helicobacter pylori Strains Isolated from Patients with Iron-Deficiency Anemia

Recent studies have suggested a link between iron-deficiency anemia and Helicobacter pylori infection. In the current study, strains of H. pylori derived from patients with iron-deficiency anemia showed enhanced Fe ion uptake and Fe ion-dependent rapid growth compared with those from patients with n...

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Bibliographic Details
Published inClinical infectious diseases Vol. 46; no. 4; pp. e31 - e33
Main Authors Yokota, Shin-ichi, Konno, Mutsuko, Mino, Emi, Sato, Kohei, Takahashi, Michiko, Fujii, Nobuhiro
Format Journal Article
LanguageEnglish
Published United States The University of Chicago Press 15.02.2008
Subjects
Adolescent
Anemia, Iron-Deficiency - complications
Anemia, Iron-Deficiency - etiology
Child
Female
Helicobacter Infections - complications
Helicobacter Infections - microbiology
Helicobacter pylori
Helicobacter pylori - isolation & purification
Helicobacter pylori - metabolism
Humans
Iron - metabolism
Male
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Summary:Recent studies have suggested a link between iron-deficiency anemia and Helicobacter pylori infection. In the current study, strains of H. pylori derived from patients with iron-deficiency anemia showed enhanced Fe ion uptake and Fe ion-dependent rapid growth compared with those from patients with non-iron-deficiency anemia. H. pylori with enhanced Fe ion-uptake ability may be a causative factor for iron-deficiency anemia.
Bibliography:ark:/67375/HXZ-08GKQBHL-W
istex:919D25E4ED53BB422277FDBAC5B08810179808ED
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1058-4838
1537-6591
DOI:10.1086/526784