Translocation t(12;13)(p13.3;q12.2) is Not Restricted to Lymphoid Malignancies; Report of a Further Case with Hypereosinophilia

We report two cases of t(12;13)(p13;q12). One was found in a lymphoid disorder, as previously described, while the second was observed in a myeloproliferative syndrome with hypereosinophilia. As t(12;13) has already been described in association with hypereosinophilia in a case of acute lymphoblasti...

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Bibliographic Details
Published inLeukemia & lymphoma Vol. 4; no. 3; p. 211
Main Authors Huret, J L, Brizard, A, Benz-Lemoine, E, Babin, P, Desmarest, M C, Demeure, L, Tanzer, J
Format Journal Article
LanguageEnglish
Published United States 1991
Subjects
Chromosome 12
hypereosinophilia
t(12;13)
myeloid malignancy
chromosome 13
lymphoid malignancy
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Summary:We report two cases of t(12;13)(p13;q12). One was found in a lymphoid disorder, as previously described, while the second was observed in a myeloproliferative syndrome with hypereosinophilia. As t(12;13) has already been described in association with hypereosinophilia in a case of acute lymphoblastic leukaemia, we suggest that the association of t(12;13) with hypereosinophilia is not random.
ISSN:1042-8194
DOI:10.3109/10428199109068067