High pressure solid–liquid equilibria of fatty acids

• Published in: Fluid phase equilibria Vol. 253; no. 2; pp. 118 - 123
• Main Authors: Costa, Mariana C., Krähenbühl, M.A., Meirelles, Antonio J.A., Daridon, J.L., Pauly, J., Coutinho, J.A.P.
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.05.2007; Elsevier Science; Elsevier
• Subjects: Caprylic acid; Chemical Physics; Chemistry; Exact sciences and technology; General and physical chemistry; High pressure; Lauric acid; Liquid-solid equilibria; Modeling; Myristic acid; Phase diagrams; Phase equilibria; Physics; Solid–liquid equilibrium; Phase diagrams; Caprylic acid; Solid–liquid equilibrium; Myristic acid; Lauric acid; Modeling; High pressure; Phase diagram; Binary system; Liquid solid equilibrium; Fatty acids; Octanoic acid; Antifungal agent; Pressure effect; Solid-liquid equilibrium; Carboxylic acid; Saturated fatty acid; Phase equilibrium
• ISSN: 0378-3812; 1879-0224
• DOI: 10.1016/j.fluid.2007.02.007

The solid–liquid phase diagrams of two binary mixtures of saturated fatty acids, formed by caprylic acid (C 8:0) + myristic acid (C 14:0) and lauric acid (C 12:0) + myristic acid (C 14:0), were measured using high pressure microscopy in the range of 0.1–90 MPa. It is shown that unlike for other long chain alkyl compounds such as alkanes the phase diagrams are only slightly affected by the pressure, even in very large pressure ranges such as studied in this work. The modeling of the measured phase diagrams was attempted using an approach previously developed by the authors for n-alkane mixtures. It is here shown that this model can provide an accurate description of the high pressure solid–liquid equilibrium of fatty acid mixtures.