Erythroid cells in suppressing leukemia cell growth

• Published in: Leukemia & lymphoma Vol. 46; no. 9; pp. 1353 - 1356
• Main Authors: Seledtsov, VI, Seledtsova, GV, Samarin, DM, Senyukov, VV, Poveschenko, OV, Felde, MA, Kozlov, VA
• Format: Journal Article
• Language: English
• Published: United States Informa UK Ltd 01.09.2005; Taylor & Francis
• Subjects: Animals; Bone Marrow Cells - physiology; Cell Division - drug effects; Cells, Cultured; Erythroid cell; Erythroid Cells - cytology; Erythropoietin - pharmacology; leukemia growth inhibition; Leukemia L1210 - pathology; Leukemia, Experimental - pathology; Leukemia, Experimental - prevention & control; Mice; Mice, Inbred Strains; Tumor Cells, Cultured

This paper indicates that murine nucleated erythroid cells (EC) are able to reduce, in a dose-dependent manner, the proliferation of both L1210 lymphoma and P815 mastocytoma cells and that the leukemia cell growth inhibitory activity of unseparated bone marrow (BM) cells may be markedly augmented by...