Pulmonary artery banding in complete atrioventricular septal defect

• Published in: The Journal of thoracic and cardiovascular surgery Vol. 159; no. 4; pp. 1493 - 1503.e3
• Main Authors: Devlin, Paul J., Jegatheeswaran, Anusha, McCrindle, Brian W., Karamlou, Tara, Blackstone, Eugene H., Williams, William G., DeCampli, William M., Mertens, Luc, Fackoury, Cheryl T., Eghtesady, Pirooz, Jacobs, Jeffrey P., Baffa, Jeanne M., Fleishman, Craig E., Dodge-Khatami, Ali, Pizarro, Christian, Pourmoghadam, Kamal, Cohen, Meryl S., Meyer, David B., Overman, David M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.04.2020
• Subjects: AVSD; Cohort Studies; complete atrioventricular septal defect; Echocardiography; Female; Heart Septal Defects - diagnostic imaging; Heart Septal Defects - mortality; Heart Septal Defects - surgery; Humans; Infant; Male; Pulmonary Artery - surgery; pulmonary artery banding; Reoperation; Survival Rate; Treatment Outcome; complete atrioventricular septal defect; PAB; STS; pulmonary artery banding; AVVI; AVSD; CHSS; PDA
• ISSN: 0022-5223; 1097-685X
• DOI: 10.1016/j.jtcvs.2019.09.019

To analyze outcomes after pulmonary artery banding (PAB) in complete atrioventricular septal defect (AVSD), with a focus on surgical pathway outcome and timing, survival, and atrioventricular valve function. PAB was performed in 50 of 474 infants (11%) from 28 institutions between 2012 and 2018 at a median age of 1.1 months. The median duration of follow-up was 2.1 years. Atrioventricular valve function was assessed by review of pre-PAB and predischarge echocardiograms (median, 9 days postoperatively). Competing-risks methodology was used to analyze the risks for biventricular repair, univentricular repair, and death. At 2 years, the proportions of patients who underwent biventricular repair, univentricular repair, and death were 68%, 13%, and 12%, respectively, with 8% awaiting definitive repair. After PAB, atrioventricular valve regurgitation decreased in 14 infants and increased in 10, but the distribution of regurgitation severity did not change significantly in the total cohort or subgroups. The intended management plan at PAB was deferred biventricular/univentricular decision (23 infants), 2-stage biventricular repair (24 infants), and univentricular repair (3 infants). Among the 24 infants intended for biventricular repair, 23 achieved biventricular repair and 1 died before repair. Survival at 4 years after biventricular repair among patients with previous PAB (93%) was similar to the 4-year survival of the patients who underwent primary biventricular repair (91%; n = 333). PAB is a successful strategy in complete AVSD to bridge to biventricular repair and has similar post-biventricular repair survival to primary biventricular repair. Changes in atrioventricular valve regurgitation after PAB were variable.