Transition metal catalyzed asymmetric cyclopropanation via diazo decomposition: Ligand architecture defining stereoselectivity

• Published in: Synthetic communications Vol. 48; no. 16; pp. 2003 - 2036
• Main Authors: Roy, Amalesh, Goswami, S. P., Sarkar, Amitabha
• Format: Journal Article
• Language: English
• Published: Philadelphia Taylor & Francis 18.08.2018; Taylor & Francis Ltd
• Subjects: Alkenes; Asymmetric cyclopropanation; Catalysis; chiral ligand; Coordination compounds; Decomposition; diazo decomposition; Enantiomers; ligand symmetry; Ligands; Literature reviews; Organic compounds; Stereoselectivity; Substrates; Transition metal compounds

Asymmetric cyclopropanation of alkenes through diazo decomposition mediated by transition metal complexes is a widely investigated catalytic reaction to obtain cyclopropanes where high enantioselectivity is achieved by optimizing metal-ligand combination. Instead of a chronological listing of develo...