Low ambient temperature as a novel risk factor of oral diseases: A time-series study

• Published in: The Science of the total environment Vol. 810; p. 152229
• Main Authors: Qian, Yifeng, Gao, Ya, Cai, Binxin, Zhang, Wenbin, Wang, Xudong, Chen, Renjie
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.03.2022
• Subjects: Aged; ambient temperature; China; China - epidemiology; Cold Temperature; confidence interval; health information; Hot Temperature; Humans; Lag patterns; Low ambient temperature; Middle Aged; Oral diseases; pain; periodontitis; Risk Factors; seasonal variation; Seasons; Temperature; time series analysis; Time series study; China; Lag patterns; Oral diseases; Time series study; Low ambient temperature
• ISSN: 0048-9697; 1879-1026; 1879-1026
• DOI: 10.1016/j.scitotenv.2021.152229

The seasonal variation of oral diseases has been observed in life, but the influences of oral diseases associated with non-optimal ambient temperature were unknown. To examine whether non-optimum ambient temperature is associated with increased risks of oral diseases. We conducted a time series study based on outpatient data from the Shanghai Health Information Center, containing all public hospitals in Shanghai from 2016 to 2019. Generalized additive models with distributed lagged nonlinear models were applied to fit the data. A total of 3,882,636 outpatient cases of oral diseases were collected. Low temperature (<7 °C) posed increased risks for oral diseases. Daily temperature above 7 °C had no effect on oral diseases. The excess risks were present on the lag 1 day and lasted till lag 7 day. Relative to referent temperatures, the cumulative risks of total oral diseases, pulpitis, periodontitis, gum pain, stomatitis, and glossitis at extreme low temperature (−3 °C, 1st percentile) over lag 0–7 day were 1.92 (95% confidence interval, CI: 1.40, 2.63), 2.40 (95% CI: 1.78, 3.25), 1.62 (95% CI: 1.15, 2.29), 1.75 (95% CI: 1.08, 2.83), 1.81 (95% CI: 1.30, 2.53), and 2.22 (95% CI: 1.23, 3.99). These associations were larger in patients who were above age 60. This study provided novel epidemiological evidence that low ambient temperature may increase the risks of oral diseases. The temperature thresholds for eight oral diseases range from 3 to 7 °C. The excess risks could last for 7 days and were larger in older patients. [Display omitted] •The associations of ambient temperature and oral diseases have rarely been studied.•Low temperature (<7 °C) posed increased risks for oral diseases.•Temperature thresholds for eight oral diseases range from 3 to 7 °C.•The excess risks were present on the lag 1 day and could last 7 days.•These associations were larger in patients who were above age 60.