Toxicological Significance of Enzyme Activities in Profenofos-Resistant Tobacco Budworms,Heliothis virescens(F.)

• Published in: Pesticide biochemistry and physiology Vol. 58; no. 1; pp. 23 - 33
• Main Authors: Harold, John A., Ottea, James A.
• Format: Journal Article
• Language: English
• Published: San Diego, CA Elsevier Inc 01.05.1997; Elsevier
• Subjects: ACETILCOLINESTERASA; ACETYLCHOLINESTERASE; ACTIVIDAD ENZIMATICA; ACTIVITE ENZYMATIQUE; Biological and medical sciences; Chemical control; Control; ENZYMIC ACTIVITY; ESTERASAS; ESTERASE; ESTERASES; Fundamental and applied biological sciences. Psychology; GLUTATHIONE TRANSFERASE; HELIOTHIS VIRESCENS; INHIBICION; INHIBITION; INSECTICIDAS; INSECTICIDE; INSECTICIDES; LARVAE; LARVAS; LARVE; Phytopathology. Animal pests. Plant and forest protection; PROFENOFOS; Protozoa. Invertebrates; RESISTANCE AUX PRODUITS CHIMIQUES; RESISTANCE MECHANISMS; RESISTANCE TO CHEMICALS; RESISTENCIA A PRODUCTOS QUIMICOS; STRAINS; SUSCEPTIBILITY; TRANSFERASAS; TRANSFERASE; TRANSFERASES; Louisiana; United States; North America; America; Malvaceae; Natural population; PROFENOFOS; Entomology; Toxicity; Insecta; Biochemistry; Esterases; Acetylcholinesterase; Fiber crop; Site of action; Target; Pest; Phytophagous; Pest management; Enzymatic activity; Glutathione transferase; Dicotyledones; Angiospermae; Chemical control; Pesticide resistance; Mechanism of action; Phytopharmacology; Subtropical zone; Laboratory study; Heliothis virescens; Unspecific monooxygenase; Enzyme; Transferases; Detoxication; Metabolism; Carboxylic ester hydrolases; Sensitivity resistance; Larva; Arthropoda; Lepidoptera; Hydrolases; Gossypium hirsutum; Spermatophyta; Noctuidae; Oxidoreductases; Invertebrata
• ISSN: 0048-3575; 1095-9939
• DOI: 10.1006/pest.1997.2283

Resistance to profenofos and activities of enzymes associated with metabolism of organophosphorus insecticides were measured in larvae of the tobacco budworm,Heliothis virescens(F.), that were field-collected from Louisiana during the 1995 cotton growing season. High frequencies of profenofos resistance were recorded in all field-collected strains and were strongly correlated with esterase activity and moderately correlated with glutathioneS-transferase activity toward 1-chloro-2,4-dinitrobenzene. Mean levels of acetylcholinesterase sensitivity to inhibition by chlorpyrifos oxon were lower in some field strains than that of an insecticide-susceptible strain; however, acetylcholinesterase sensitivity and resistance were poorly correlated in all field strains. Finally, there was no correlation between resistance and activities of P450-monooxygenase towardp-nitroanisole or glutathioneS-transferase toward 1,2-dichloro-4-nitrobenzene. These results suggest possible contributions of both metabolic and target site mechanisms toward profenofos resistance in this insect.