Role of the E3 Ubiquitin Ligase TRIM4 in Predicting the Prognosis of Hepatocellular Carcinoma

• Published in: Journal of Cancer Vol. 11; no. 14; pp. 4007 - 4014
• Main Authors: Dong, Zhao-Ru, Zhou, Wei, Sun, Dong, Yan, Yu-Chuan, Yang, Chun-Cheng, Yang, Ya-Fei, Li, Hai-Chao, Zhi, Xu-Ting, Li, Tao
• Format: Journal Article
• Language: English
• Published: Australia Ivyspring International Publisher Pty Ltd 01.01.2020; Ivyspring International Publisher
• Subjects: Antibodies; Cell cycle; Enzymes; Liver cancer; Medical prognosis; Patients; Proteins; Research Paper; Statistical analysis; Tumorigenesis; Tumors; progression; E3 ubiquitin ligase; TRIM4; hepatocellular carcinoma

The E3 ubiquitin ligase TRIM4 has been reported to regulate the assembly of the antiviral signalling complex, induce mitochondrial aggregation and sensitize cells to H O -induced death. However, the relationship between TRIM4 and human malignancies, including hepatocellular carcinoma (HCC), is uncle...