Electrode material fabricated by loading cerium oxide nanoparticles on reduced graphene oxide and its application in electrochemical sensor for tryptophan

• Published in: Journal of alloys and compounds Vol. 842; p. 155934
• Main Authors: Zhang, Ji-Wei, Zhang, Xuan
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 25.11.2020; Elsevier BV
• Subjects: Biological properties; Cerium oxide nanoparticles; Cerium oxides; Chemical sensors; Electrochemical analysis; Electrochemical impedance spectroscopy; Electrochemical sensor; Electrode materials; Electrodes; Graphene; Nanocomposites; Nanoparticles; Photoelectrons; Reduced graphene oxide; Sensors; Spectrum analysis; Tryptophan; Voltammetry; X ray photoelectron spectroscopy; Tryptophan; Cerium oxide nanoparticles; Reduced graphene oxide; Electrochemical sensor
• ISSN: 0925-8388; 1873-4669
• DOI: 10.1016/j.jallcom.2020.155934

Facile fabrication of advanced electrode material is highly desired for novel electrochemical sensor development. Herein, cerium oxide (CeO2) nanoparticles were successfully loaded on reduced graphene oxide (RGO) by one-step hydrothermal synthesis approach, and the as-prepared nanocomposite (CeO2/RGO) was used as novel electrode material for electrochemical detection of tryptophan. The structure and composition of CeO2/RGO nanocomposite were fully characterized by transmission electron microscope (TEM), X-ray powder diffractometry (XRD) and X-ray photoelectron spectroscopy (XPS), respectively. The electrochemical properties were characterized by several techniques such as cyclic voltammetry (CV), differential pulse voltammetry (DPV), and electrochemical impedance spectroscopy (EIS). It was found that the CeO2/RGO nanocomposite electrode exhibits an enhanced peak current response compared with individual CeO2 or RGO material. The electrochemical sensor based CeO2/RGO material showed a selective and sensitive response toward tryptophan determination, and a linear range of 0.2–25 μM with a detection limit of 80 nM (S/N = 3) was achieved. The present electrochemical sensor displayed an excellent stability and reproducibility, and was successfully applied in the determination of tryptophan in real food and biological samples. CeO2 was loaded on reduced graphene oxide (CeO2-RGO) and used as active electrode material for electrochemical detection of tryptophan in food and biological samples. [Display omitted] •CeO2 loaded on reduced graphene oxide (CeO2-RGO) composite was facilely fabricated by a hydrothermal reduction approach.•The CeO2-RGO was used as a novel electrode material for tryptophan detection.•The present electrochemical sensor exhibited improved analytical performance.•The CeO2-RGO electrode material has been successfully used for tryptophan detection in milk and bovine serum samples.