Managing surgical relapse risk in acquired thrombotic thrombocytopenic purpura: a systematic review

•Thrombotic thrombocytopenic purpura (TTP) may relapse after surgery.•In a systematic review, we assessed preoperative TTP prophylaxis.•Pre-emptive ADAMTS-13 activity measurement prior to surgery may improve relapse risk.•Preoperative TTP prophylaxis may lower surgical relapse risk.

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Bibliographic Details
Published inResearch and practice in thrombosis and haemostasis Vol. 8; no. 5; p. 102478
Main Authors Pinheiro Maux Lessa, Morgana, Soares Ferreira Junior, Alexandre, Graton, Margaret, Simon, Erin, Ledbetter, Leila, Onwuemene, Oluwatoyosi A.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.07.2024
Elsevier
Subjects
precipitating factors
relapse
Research Letter
surgery
surgical procedures
thrombotic thrombocytopenic purpura
surgical procedures
thrombotic thrombocytopenic purpura
precipitating factors
relapse
surgery
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Summary:•Thrombotic thrombocytopenic purpura (TTP) may relapse after surgery.•In a systematic review, we assessed preoperative TTP prophylaxis.•Pre-emptive ADAMTS-13 activity measurement prior to surgery may improve relapse risk.•Preoperative TTP prophylaxis may lower surgical relapse risk.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:2475-0379
2475-0379
DOI:10.1016/j.rpth.2024.102478