ACG Clinical Guideline: Disorders of the Hepatic and Mesenteric Circulation

• Published in: The American journal of gastroenterology Vol. 115; no. 1; pp. 18 - 40
• Main Authors: Simonetto, Douglas A, Singal, Ashwani K, Garcia-Tsao, Guadalupe, Caldwell, Stephen H, Ahn, Joseph, Kamath, Patrick S
• Format: Journal Article
• Language: English
• Published: United States Wolters Kluwer Health Medical Research, Lippincott Williams & Wilkins 01.01.2020
• Subjects: Anticoagulants; Blood platelets; Clinical medicine; Endothelium; Gastroenterology; Humans; Liver - blood supply; Liver cancer; Liver Circulation; Liver cirrhosis; Liver diseases; Liver Diseases - etiology; Liver Diseases - physiopathology; Mesentery - blood supply; Practice Guidelines as Topic; Societies, Medical; Splanchnic Circulation; Thrombosis; United States; Vascular Diseases - complications; Vascular Diseases - therapy; Veins & arteries; United States
• ISSN: 0002-9270; 1572-0241
• DOI: 10.14309/ajg.0000000000000486

Disorders of the mesenteric, portal, and hepatic veins and mesenteric and hepatic arteries have important clinical consequences and may lead to acute liver failure, chronic liver disease, noncirrhotic portal hypertension, cirrhosis, and hepatocellular carcinoma. Although literature in the field of vascular liver disorders is scant, these disorders are common in clinical practice, and general practitioners, gastroenterologists, and hepatologists may benefit from expert guidance and recommendations for management of these conditions. These guidelines represent the official practice recommendations of the American College of Gastroenterology. Key concept statements based on author expert opinion and review of literature and specific recommendations based on PICO/GRADE analysis have been developed to aid in the management of vascular liver disorders. These recommendations and guidelines should be tailored to individual patients and circumstances in routine clinical practice.