C-Reactive Protein Decrease After Postbariatric Abdominoplasty

• Published in: Inflammation Vol. 35; no. 1; pp. 316 - 320
• Main Authors: Cintra, Wilson, Modolin, Miguel, Faintuch, Joel, Gemperli, Rolf, Ferreira, Marcus C.
• Format: Journal Article
• Language: English
• Published: Boston Springer US 01.02.2012; Springer Nature B.V
• Subjects: Biomedical and Life Sciences; Biomedicine; Blood Glucose - analysis; Body Mass Index; C-Reactive Protein - metabolism; Cholesterol, HDL - blood; Female; Gastric Bypass; Glucose - metabolism; Hemoglobins - analysis; Humans; Immunology; Internal Medicine; Intra-Abdominal Fat - surgery; Leukocyte Count; Lipid Metabolism; Mammaplasty; Obesity, Morbid - surgery; Pathology; Pharmacology/Toxicology; Premenopause; Reconstructive Surgical Procedures; Rheumatology; Triglycerides - blood; systemic inflammation; glucose homeostasis; bariatric surgery; subcutaneous fat; abdominoplasty; c-reactive protein; weight loss; lipid homeostasis; microinflammation
• ISSN: 0360-3997; 1573-2576
• DOI: 10.1007/s10753-011-9321-9

In a prospective study, indices of glucose homeostasis, lipid profile, and systemic inflammation were monitored after an aesthetic abdominoplasty, aiming to scrutinize the possible metabolic benefits for abdominal fat removal. Premenopausal females with substantial weight loss ( N  = 40) undergoing circumferential abdominoplasty (index group, n  = 20) or augmentation mammoplasty with mastopexy (controls, n  = 20) were recruited. All of them originally underwent Roux-en-Y gastric bypass. Variables included BMI, white blood cell count, C-reactive protein, hemoglobin, total cholesterol and fractions, triglycerides, glucose, and HbA1c. Follow-up reached 20.3 ± 13.6 months for index cases and 29.5 ± 17.4 months for controls. The metabolic and inflammatory indices improved after the bariatric surgery. Subsequent monitoring indicated a stable body weight and biochemical profile in both groups. The exceptions were HDL cholesterol and C-reactive protein, which respectively increased and diminished after the abdominoplasty, consistent with an inflammatory and metabolic advantage for this operation. This is the first long-term study in a weight-stable population to point out such a pattern after abdominoplasty.