Near-infrared heptamethine cyanines (Cy7): from structure, property to application

Heptamethine cyanine dyes (Cy7) have attracted much attention in the field of biological application due to their unique structure and attractive near infrared (NIR) photophysical properties. In this review, the influences of different modification sites on the absorption characteristics, photostabi...

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Published inOrganic & biomolecular chemistry Vol. 18; no. 46; pp. 9385 - 9397
Main Authors Feng, Lan, Chen, Weijie, Ma, Xiaoxie, Liu, Sheng Hua, Yin, Jun
Format Journal Article
LanguageEnglish
Published England Royal Society of Chemistry 07.12.2020
Subjects
Cyanine dyes
Dyes
Fluorescence
Optimization
Singlet oxygen
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Summary:Heptamethine cyanine dyes (Cy7) have attracted much attention in the field of biological application due to their unique structure and attractive near infrared (NIR) photophysical properties. In this review, the influences of different modification sites on the absorption characteristics, photostability, Stokes shift, fluorescence characteristics, water solubility, and singlet oxygen generation efficiency of this class of dyes are summarized, and the application development of the corresponding dyes in the field of biological application is introduced, which will provide a reference for the optimization and improvement of heptamethine cyanine dyes in the future. Heptamethine cyanine dyes (Cy7) have attracted much attention in the field of biological application due to their unique structure and attractive near infrared (NIR) photophysical properties.
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ISSN:1477-0520
1477-0539
1477-0539
DOI:10.1039/d0ob01962c