Effect of Oral Enrofloxacin and Florfenicol on Pigs Experimentally Infected with Actinobacillus pleuropneumoniae Serotype 1
Summary This study was carried out to compare the efficacy of two oral anti‐microbials as metaphylactic medication to pigs inoculated with Actinobacillus pleuropneumoniae serotype 1. Forty‐two pigs with an average weight of 22.64 kg were randomly assigned to three treatment groups: group F was given...
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Published in | Journal of veterinary medicine. Series A Vol. 50; no. 5; pp. 259 - 263 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
Berlin, Germany
Blackwell Verlag GmbH
01.06.2003
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Abstract | Summary
This study was carried out to compare the efficacy of two oral anti‐microbials as metaphylactic medication to pigs inoculated with Actinobacillus pleuropneumoniae serotype 1. Forty‐two pigs with an average weight of 22.64 kg were randomly assigned to three treatment groups: group F was given doses of 40 ppm of florfenicol, group E received 150 ppm of enrofloxacin and group C received no medication. Groups F and E received medicated feed 12 h before being inoculated and for 7 days after inoculation. All the pigs were inoculated by aerosol, with 2 × 107 CFU/ml of A. pleuropneumoniae serotype 1 each. The average body temperature was higher in group C than in groups E and F, between 12 and 96 h after inoculation (P < 0.05). No differences were found between groups F and E in respiration pattern, nasal secretion and general condition (P > 0.05); however, differences were found in group C for respiration pattern and general condition (P < 0.05), 12 h after inoculation. There was no mortality in groups F and E, whereas a 50% mortality was recorded in group C during the first 48 h after inoculation (P < 0.05). Necropsies and bacterial cultures were performed 12 days after inoculation. Lesions were observed in five pigs of group F (35.71%) with an average damage of 1.16%; in four pigs of group E (28.57%) with 1.24%; and in 13 animals in group C (92.85%) with 34.5% of affected lung tissue (P < 0.05). The infective agent was cultured from various organs of animals in groups F and C, but not from those in group E. |
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AbstractList | Summary
This study was carried out to compare the efficacy of two oral anti‐microbials as metaphylactic medication to pigs inoculated with Actinobacillus pleuropneumoniae serotype 1. Forty‐two pigs with an average weight of 22.64 kg were randomly assigned to three treatment groups: group F was given doses of 40 ppm of florfenicol, group E received 150 ppm of enrofloxacin and group C received no medication. Groups F and E received medicated feed 12 h before being inoculated and for 7 days after inoculation. All the pigs were inoculated by aerosol, with 2 × 107 CFU/ml of A. pleuropneumoniae serotype 1 each. The average body temperature was higher in group C than in groups E and F, between 12 and 96 h after inoculation (P < 0.05). No differences were found between groups F and E in respiration pattern, nasal secretion and general condition (P > 0.05); however, differences were found in group C for respiration pattern and general condition (P < 0.05), 12 h after inoculation. There was no mortality in groups F and E, whereas a 50% mortality was recorded in group C during the first 48 h after inoculation (P < 0.05). Necropsies and bacterial cultures were performed 12 days after inoculation. Lesions were observed in five pigs of group F (35.71%) with an average damage of 1.16%; in four pigs of group E (28.57%) with 1.24%; and in 13 animals in group C (92.85%) with 34.5% of affected lung tissue (P < 0.05). The infective agent was cultured from various organs of animals in groups F and C, but not from those in group E. Summary This study was carried out to compare the efficacy of two oral anti‐microbials as metaphylactic medication to pigs inoculated with Actinobacillus pleuropneumoniae serotype 1. Forty‐two pigs with an average weight of 22.64 kg were randomly assigned to three treatment groups: group F was given doses of 40 ppm of florfenicol, group E received 150 ppm of enrofloxacin and group C received no medication. Groups F and E received medicated feed 12 h before being inoculated and for 7 days after inoculation. All the pigs were inoculated by aerosol, with 2 × 10 7 CFU/ml of A. pleuropneumoniae serotype 1 each. The average body temperature was higher in group C than in groups E and F, between 12 and 96 h after inoculation ( P < 0.05). No differences were found between groups F and E in respiration pattern, nasal secretion and general condition ( P > 0.05); however, differences were found in group C for respiration pattern and general condition ( P < 0.05), 12 h after inoculation. There was no mortality in groups F and E, whereas a 50% mortality was recorded in group C during the first 48 h after inoculation ( P < 0.05). Necropsies and bacterial cultures were performed 12 days after inoculation. Lesions were observed in five pigs of group F (35.71%) with an average damage of 1.16%; in four pigs of group E (28.57%) with 1.24%; and in 13 animals in group C (92.85%) with 34.5% of affected lung tissue ( P < 0.05). The infective agent was cultured from various organs of animals in groups F and C, but not from those in group E. This study was carried out to compare the efficacy of two oral anti-microbials as metaphylactic medication to pigs inoculated with Actinobacillus pleuropneumoniae serotype 1. Forty-two pigs with an average weight of 22.64 kg were randomly assigned to three treatment groups: group F was given doses of 40 ppm of florfenicol, group E received 150 ppm of enrofloxacin and group C received no medication. Groups F and E received medicated feed 12 h before being inoculated and for 7 days after inoculation. All the pigs were inoculated by aerosol, with 2 x 10(7) CFU/ml of A. pleuropneumoniae serotype 1 each. The average body temperature was higher in group C than in groups E and F, between 12 and 96 h after inoculation (P < 0.05). No differences were found between groups F and E in respiration pattern, nasal secretion and general condition (P > 0.05): however, differences were found in group C for respiration pattern and general condition (P < 0.05), 12 h after inoculation. There was no mortality in groups F and E, whereas a 50% mortality was recorded in group C during the first 48 h after inoculation (P < 0.05). Necropsies and bacterial cultures were performed 12 days after inoculation. Lesions were observed in five pigs of group F (35.71%) with an average damage of 1.16%; in four pigs of group E (28.57%) with 1.24%; and in 13 animals in group C (92.85%) with 34.5% of affected lung tissue (P < 0.05). The infective agent was cultured from various organs of animals in groups F and C, but not from those in group E. |
Author | Martínez-Gamba, R. Herradora, L. M. A. |
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References | Glattleider, D., H. Bossow, J. Sommer, A. Laval, J. L. Abric, L. Goosens, and E. Lockwood, 2000: Comparative efficacy of florfenicol and oxytetracycline LA in the treatment of naturally occurring swine respiratory disease in Europe. Proc. 16th IPVS Congress, p. 107, Melbourne, Australia. Gutiérrez, P. J. A., E. G. Jiménez, G. H. Ramírez, P. E. Galván, and A. Mercadillo, 1995: Estudio de dos Técnicas serológicas para la tipificación de Actinobacillus pleuropneumoniae. Veterinaria México 26, 41-43. Osborne, A. D., J. R. Saunders, T. K. Sebunya, P. Willson, and G. H. Green, 1985: A simple aerosol for experimental reproduction of respiratory disease in pigs and other species. Can. J. Comp. Med. V. 49, 434-435. Asawa, T., H. Kobayashi, K. Mitani, N. Ito, and T. Morozumi, 1995: Serotypes and antimicrobial of Actinobacillus pleuropneumoniae isolated from piglets with pleuropneumonia. J. Vet. Med. Sci. 57, 757-759. Mittal, K. R., R. Higgins, and S. Larivier, 1982: Evaluation of slide agglutination and ring precipitation test for capsular serotyping of Haemophilus pleuropneumoniae. J. Clin. Microbiol. 17, 1019-1023. Ueda, Y., and Y. Suenaga, 1995: In vitro antibacterial activity of florfenicol against Actinobacillus pleuropneumoniae. J. Vet. Med. Sci. 57, 363-364. Stephano, A., and C. R. Díaz, and R. F. Vázquez, 1992: Experiencias con enrofloxacina contra la pleuroneumonía por A. pleuropneumoniae. Medicina Veterinaria 9, 412-416. Biberstein, E. L., A. Gunnarson, and B. Hurvell, 1977: Cultural and biochemical criteria for the identification of Haemophilus spp from swine. Am. J. Vet. Res. 38, 7-11. Ueda, Y., S. Ohtsuki, and N. Narakawa, 1995: Efficacy of florfenicol on experimental Actinobacillus pleuropneumoniae in pigs. J. Vet. Med. Sci. 57, 261-265. Mestorino, N., J. Pesoa, E. Turic, and J. Errecalde, 1999: Florfenicol: pharmacological aspects. Vet. Argentina 16, 127-141. Vancutsen, P. M., J. G. Babish, and W. S. Schwark, 1990: The fluoroquinolone antimicrobials: structure, antimicrobial activity, pharmacokinetics, clinical use in domestic animals and toxicity. Cornell Vet. 80, 173-186. Morrison, R. B., H. D. Hilley, and A. D. Leman, 1985: Comparison of methods for assessing the prevalence and extent of pneumonia in market weight swine. Can. Vet. J. 26, 381-384. Steel, R. G. D., and J. H. Torrie, 1984: Principles and Procedures of Statistics, 2nd edn. McGraw-Hill, NY, USA. Salmon, S. A., J. L. Watts, C. A. Case, L. J. Hoffman, H. C. Wegener, and R. J. Yancey, 1993: Comparison of MICs of Ceftiofur and other antimicrobial agents against bacterial pathogens of swine from the US, Canada, and Denmark. J. Clin. Microbiol. 33, 2435-2444. Zuñiga, H. J. F., O. M. Trujillo, and D. J. Doporto, 1995: Efecto de dos quinolonas (nicotinato de Norfloxacina y Enrofloxacina) y del trimetoprim en combinación con sulfametoxazol en el tratamiento de enfermedades respiratorias (Actinobacillus pleuropneumoniae). Veterinaria México 26, 95-101. Miller, D. J. S., 1991: New drugs and medications. Pig Vet. J. 27, 184-192. Morrison, D. F., 1976: Multivariate Statistical Methods, 2nd edn. Mc Graw-Hill Book Company. New York. Gutiérrez, C. B., S. Vadillo, and F. Rodríguez, 1993: In vitro susceptibility of Actinobacillus pleuropneumoniae strains to 42 antimicrobial agents. Am. J. Vet. Res. 54, 546-550. Wallgren, P., T. Segall, A. Pedersenmornen, and A. Gunnarsson, 1999: Experimental infections with Actinobacillus pleuropneumoniae in pigs-I. Comparison of five different parenteral antibiotic treatments. J. Vet. Med. B. 46, 249-260. National Research Council, 1998: Nutrient Requirements of Domestic Animals. Nutrient Requirements of Swine, 9th edn. National Academy Press, Washington USA. 1990; 1 1992; 9 1991; 27 1982; 17 2000 1995; 26 1977; 38 1995; 57 1993; 33 1993; 54 1999; 16 1976 1998 1999; 46 1984 1985; 26 1990; 80 1985; 49 1999 Morrison D. F. (e_1_2_17_11_1) 1976 Salmon S. A. (e_1_2_17_16_1) 1993; 33 e_1_2_17_2_1 Stephano A. (e_1_2_17_18_1) 1990 e_1_2_17_21_1 Mestorino N. (e_1_2_17_8_1) 1999; 16 e_1_2_17_22_1 Palacios A. J. M. (e_1_2_17_15_1) 2000 Ciprian C. A. (e_1_2_17_4_1) 1990 National Research Council (e_1_2_17_13_1) 1998 Mittal K. R. (e_1_2_17_10_1) 1982; 17 Gutiérrez P. J. A. (e_1_2_17_7_1) 1995; 26 Stephano A. (e_1_2_17_19_1) 1992; 9 Morrison R. B. (e_1_2_17_12_1) 1985; 26 Wallgren P. (e_1_2_17_24_1) 1999; 46 Miller D. J. S. (e_1_2_17_9_1) 1991; 27 Vancutsen P. M. (e_1_2_17_23_1) 1990; 80 Gutiérrez C. B. (e_1_2_17_6_1) 1993; 54 Osborne A. D. (e_1_2_17_14_1) 1985; 49 Biberstein E. L. (e_1_2_17_3_1) 1977; 38 Glattleider D. (e_1_2_17_5_1) 2000 Steel R. G. D. (e_1_2_17_17_1) 1984 Taylor D. J. (e_1_2_17_20_1) 1999 Zuñiga H. J. F. (e_1_2_17_25_1) 1995; 26 |
References_xml | – start-page: 343 year: 1999 end-page: 354 – volume: 17 start-page: 1019 year: 1982 end-page: 1023 article-title: Evaluation of slide agglutination and ring precipitation test for capsular serotyping of publication-title: J. Clin. Microbiol. – volume: 26 start-page: 381 year: 1985 end-page: 384 article-title: Comparison of methods for assessing the prevalence and extent of pneumonia in market weight swine publication-title: Can. Vet. J. – volume: 26 start-page: 41 year: 1995 end-page: 43 article-title: Estudio de dos Técnicas serológicas para la tipificación de publication-title: Veterinaria México – year: 1984 – volume: 27 start-page: 184 year: 1991 end-page: 192 article-title: New drugs and medications publication-title: Pig Vet. J. – volume: 57 start-page: 363 year: 1995 end-page: 364 article-title: In vitro antibacterial activity of florfenicol against publication-title: J. Vet. Med. Sci. – volume: 1 start-page: 29 year: 1990 end-page: 42 – volume: 16 start-page: 127 year: 1999 end-page: 141 article-title: Florfenicol: pharmacological aspects publication-title: Vet. Argentina – volume: 38 start-page: 7 year: 1977 end-page: 11 article-title: Cultural and biochemical criteria for the identification of spp from swine publication-title: Am. J. Vet. Res. – volume: 57 start-page: 757 year: 1995 end-page: 759 article-title: Serotypes and antimicrobial of isolated from piglets with pleuropneumonia publication-title: J. Vet. Med. Sci. – volume: 49 start-page: 434 year: 1985 end-page: 435 article-title: A simple aerosol for experimental reproduction of respiratory disease in pigs and other species publication-title: Can. J. Comp. Med. V. – volume: 9 start-page: 412 year: 1992 end-page: 416 article-title: Experiencias con enrofloxacina contra la pleuroneumonía por publication-title: Medicina Veterinaria – start-page: 17 year: 2000 end-page: 20 – volume: 1 start-page: 43 year: 1990 end-page: 60 – start-page: 107 year: 2000 – volume: 33 start-page: 2435 year: 1993 end-page: 2444 article-title: Comparison of MICs of Ceftiofur and other antimicrobial agents against bacterial pathogens of swine from the US, Canada, and Denmark publication-title: J. Clin. Microbiol. – volume: 80 start-page: 173 year: 1990 end-page: 186 article-title: The fluoroquinolone antimicrobials: structure, antimicrobial activity, pharmacokinetics, clinical use in domestic animals and toxicity publication-title: Cornell Vet. – volume: 26 start-page: 95 year: 1995 end-page: 101 article-title: Efecto de dos quinolonas (nicotinato de Norfloxacina y Enrofloxacina) y del trimetoprim en combinación con sulfametoxazol en el tratamiento de enfermedades respiratorias ( ) publication-title: Veterinaria México – volume: 46 start-page: 249 year: 1999 end-page: 260 article-title: Experimental infections with in pigs‐I. Comparison of five different parenteral antibiotic treatments publication-title: J. Vet. Med. B. – volume: 54 start-page: 546 year: 1993 end-page: 550 article-title: In vitro susceptibility of strains to 42 antimicrobial agents publication-title: Am. J. Vet. Res. – volume: 57 start-page: 261 year: 1995 end-page: 265 article-title: Efficacy of florfenicol on experimental in pigs publication-title: J. Vet. Med. Sci. – year: 1976 – year: 1998 – volume: 26 start-page: 95 year: 1995 ident: e_1_2_17_25_1 article-title: Efecto de dos quinolonas (nicotinato de Norfloxacina y Enrofloxacina) y del trimetoprim en combinación con sulfametoxazol en el tratamiento de enfermedades respiratorias (Actinobacillus pleuropneumoniae) publication-title: Veterinaria México contributor: fullname: Zuñiga H. J. F. – ident: e_1_2_17_2_1 doi: 10.1292/jvms.57.757 – volume: 16 start-page: 127 year: 1999 ident: e_1_2_17_8_1 article-title: Florfenicol: pharmacological aspects publication-title: Vet. Argentina contributor: fullname: Mestorino N. – volume: 49 start-page: 434 year: 1985 ident: e_1_2_17_14_1 article-title: A simple aerosol for experimental reproduction of respiratory disease in pigs and other species publication-title: Can. J. Comp. Med. V. contributor: fullname: Osborne A. D. – volume: 17 start-page: 1019 year: 1982 ident: e_1_2_17_10_1 article-title: Evaluation of slide agglutination and ring precipitation test for capsular serotyping of Haemophilus pleuropneumoniae publication-title: J. Clin. Microbiol. doi: 10.1128/jcm.15.6.1019-1023.1982 contributor: fullname: Mittal K. R. – start-page: 43 volume-title: Asociación Mexicana de Veterinarios Especialistas en Cerdos year: 1990 ident: e_1_2_17_18_1 contributor: fullname: Stephano A. – start-page: 17 volume-title: Proc 16th IPVS Congress year: 2000 ident: e_1_2_17_15_1 contributor: fullname: Palacios A. J. M. – volume: 33 start-page: 2435 year: 1993 ident: e_1_2_17_16_1 article-title: Comparison of MICs of Ceftiofur and other antimicrobial agents against bacterial pathogens of swine from the US, Canada, and Denmark publication-title: J. Clin. Microbiol. doi: 10.1128/jcm.33.9.2435-2444.1995 contributor: fullname: Salmon S. A. – ident: e_1_2_17_22_1 doi: 10.1292/jvms.57.363 – volume: 54 start-page: 546 year: 1993 ident: e_1_2_17_6_1 article-title: In vitro susceptibility of Actinobacillus pleuropneumoniae strains to 42 antimicrobial agents publication-title: Am. J. Vet. Res. contributor: fullname: Gutiérrez C. B. – volume-title: Principles and Procedures of Statistics year: 1984 ident: e_1_2_17_17_1 contributor: fullname: Steel R. G. D. – volume: 80 start-page: 173 year: 1990 ident: e_1_2_17_23_1 article-title: The fluoroquinolone antimicrobials: structure, antimicrobial activity, pharmacokinetics, clinical use in domestic animals and toxicity publication-title: Cornell Vet. contributor: fullname: Vancutsen P. M. – volume: 27 start-page: 184 year: 1991 ident: e_1_2_17_9_1 article-title: New drugs and medications publication-title: Pig Vet. J. contributor: fullname: Miller D. J. S. – ident: e_1_2_17_21_1 doi: 10.1292/jvms.57.261 – volume: 38 start-page: 7 year: 1977 ident: e_1_2_17_3_1 article-title: Cultural and biochemical criteria for the identification of Haemophilus spp from swine publication-title: Am. J. Vet. Res. contributor: fullname: Biberstein E. L. – volume-title: Nutrient Requirements of Domestic Animals. Nutrient Requirements of Swine year: 1998 ident: e_1_2_17_13_1 contributor: fullname: National Research Council – volume: 9 start-page: 412 year: 1992 ident: e_1_2_17_19_1 article-title: Experiencias con enrofloxacina contra la pleuroneumonía por A. pleuropneumoniae publication-title: Medicina Veterinaria contributor: fullname: Stephano A. – start-page: 343 volume-title: Diseases of Swine year: 1999 ident: e_1_2_17_20_1 contributor: fullname: Taylor D. J. – volume: 26 start-page: 381 year: 1985 ident: e_1_2_17_12_1 article-title: Comparison of methods for assessing the prevalence and extent of pneumonia in market weight swine publication-title: Can. Vet. J. contributor: fullname: Morrison R. B. – volume: 46 start-page: 249 year: 1999 ident: e_1_2_17_24_1 article-title: Experimental infections with Actinobacillus pleuropneumoniae in pigs‐I. Comparison of five different parenteral antibiotic treatments publication-title: J. Vet. Med. B. doi: 10.1111/j.0931-1793.1999.0_227.x contributor: fullname: Wallgren P. – start-page: 107 volume-title: Comparative efficacy of florfenicol and oxytetracycline LA in the treatment of naturally occurring swine respiratory disease in Europe year: 2000 ident: e_1_2_17_5_1 contributor: fullname: Glattleider D. – start-page: 29 volume-title: Asociación Mexicana de Veterinarios Especialistas en Cerdos year: 1990 ident: e_1_2_17_4_1 contributor: fullname: Ciprian C. A. – volume-title: Multivariate Statistical Methods year: 1976 ident: e_1_2_17_11_1 contributor: fullname: Morrison D. F. – volume: 26 start-page: 41 year: 1995 ident: e_1_2_17_7_1 article-title: Estudio de dos Técnicas serológicas para la tipificación de Actinobacillus pleuropneumoniae publication-title: Veterinaria México contributor: fullname: Gutiérrez P. J. A. |
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This study was carried out to compare the efficacy of two oral anti‐microbials as metaphylactic medication to pigs inoculated with Actinobacillus... This study was carried out to compare the efficacy of two oral anti-microbials as metaphylactic medication to pigs inoculated with Actinobacillus... Summary This study was carried out to compare the efficacy of two oral anti‐microbials as metaphylactic medication to pigs inoculated with Actinobacillus... |
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SubjectTerms | Actinobacillus Infections - drug therapy Actinobacillus Infections - veterinary Actinobacillus pleuropneumoniae - classification Actinobacillus pleuropneumoniae - pathogenicity Administration, Oral Animals Anti-Bacterial Agents - administration & dosage Anti-Bacterial Agents - therapeutic use Anti-Infective Agents - administration & dosage Anti-Infective Agents - therapeutic use Body Temperature Fluoroquinolones Male Quinolones - administration & dosage Quinolones - therapeutic use Swine Swine Diseases - drug therapy Swine Diseases - pathology Thiamphenicol - administration & dosage Thiamphenicol - analogs & derivatives Thiamphenicol - therapeutic use Treatment Outcome |
Title | Effect of Oral Enrofloxacin and Florfenicol on Pigs Experimentally Infected with Actinobacillus pleuropneumoniae Serotype 1 |
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