Single‐cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8+ αβ T lymphocytes in untreated celiac disease
We compared the αβ T‐cell receptor repertoires of CD8+ αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single‐cell sequencing. We demonstrate that the repertoires of untreated celiac disease patients were more polyclonal and more diverse than what was observed in...
Saved in:
| Published in | European journal of immunology Vol. 51; no. 6; pp. 1542 - 1545 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Germany
Wiley Subscription Services, Inc
01.06.2021
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | We compared the αβ T‐cell receptor repertoires of CD8+ αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single‐cell sequencing. We demonstrate that the repertoires of untreated celiac disease patients were more polyclonal and more diverse than what was observed in both treated patients and healthy subjects. |
|---|---|
| AbstractList | We compared the αβ T-cell receptor repertoires of CD8+ αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single-cell sequencing. We demonstrate that the repertoires of untreated celiac disease patients were more polyclonal and more diverse than what was observed in both treated patients and healthy subjects.We compared the αβ T-cell receptor repertoires of CD8+ αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single-cell sequencing. We demonstrate that the repertoires of untreated celiac disease patients were more polyclonal and more diverse than what was observed in both treated patients and healthy subjects. We compared the αβ T-cell receptor repertoires of CD8 αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single-cell sequencing. We demonstrate that the repertoires of untreated celiac disease patients were more polyclonal and more diverse than what was observed in both treated patients and healthy subjects. We compared the αβ T‐cell receptor repertoires of CD8+ αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single‐cell sequencing. We demonstrate that the repertoires of untreated celiac disease patients were more polyclonal and more diverse than what was observed in both treated patients and healthy subjects. |
| Author | Christophersen, Asbjørn Risnes, Louise F. Eggesbø, Linn M. Lundin, Knut E. A. Sollid, Ludvig M. Neumann, Ralf S. |
| Author_xml | – sequence: 1 givenname: Linn M. surname: Eggesbø fullname: Eggesbø, Linn M. organization: University of Oslo – sequence: 2 givenname: Louise F. surname: Risnes fullname: Risnes, Louise F. organization: University of Oslo and Oslo University Hospital‐ Rikshospitalet – sequence: 3 givenname: Ralf S. surname: Neumann fullname: Neumann, Ralf S. organization: University of Oslo – sequence: 4 givenname: Knut E. A. surname: Lundin fullname: Lundin, Knut E. A. organization: Oslo University Hospital‐Rikshospitalet – sequence: 5 givenname: Asbjørn surname: Christophersen fullname: Christophersen, Asbjørn organization: University of Oslo – sequence: 6 givenname: Ludvig M. orcidid: 0000-0001-8860-704X surname: Sollid fullname: Sollid, Ludvig M. email: l.m.sollid@medisin.uio.no organization: University of Oslo and Oslo University Hospital‐ Rikshospitalet |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33559929$$D View this record in MEDLINE/PubMed |
| BookMark | eNp90c1u1DAQB3ALFdFt4cgVWeKChFL8lXV8REuBokpIsJwtxxk3XjlxiBNQbjwCR14DHqQPwZPg1bYcKsHJkv2bseY_J-iojz0g9JiSM0oIewE7f8YII6JSUtxDK1oyWggq6BFaEUJFwVRFjtFJSjtCiFqX6gE65rwslWJqhX589P1VgN_fvlsIAW83H_AIA4xT9CNg05uwJJ_y3RcwIeHWX7VhwUMMiw0xv2IbuyEmP_nY4-hwO3emx76fRgODn1oIPqPNq-o5vv55_QtvcVi6oY12mSBlh-dMwUzQYLu3Fjc-gUnwEN13-Ud4dHOeok-vz7ebt8Xl-zcXm5eXhRWEy2JNHK8bU9W8MdQpwwQHKRorpRK1qzlXzHK2BucaJqgiTkompBPSEEtrVfJT9OzQdxjj5xnSpDuf9lmYHuKcNBOVlEJJrjJ9eofu4jzmELIquRS0Ksk6qyc3aq47aPQw-s6Mi77NPAN-AHaMKY3gtPWT2QeYQ_NBU6L3m9V5s_rvZnNVcafqtvG_PDv4rz7A8n-sz99dCJVn_APvYLhL |
| CitedBy_id | crossref_primary_10_1126_sciimmunol_adf4312 crossref_primary_10_1038_s41385_021_00452_0 crossref_primary_10_1146_annurev_pathmechdis_031521_032634 crossref_primary_10_1111_sji_13120 crossref_primary_10_1136_jcp_2022_208541 crossref_primary_10_1053_j_gastro_2024_02_048 crossref_primary_10_1073_pnas_2416097121 crossref_primary_10_1038_s41582_024_01025_y crossref_primary_10_1053_j_gastro_2024_03_042 |
| Cites_doi | 10.1002/eji.200425122 10.1126/science.1716785 10.4049/jimmunol.1601693 10.1084/jem.180.4.1337 10.1146/annurev-immunol-040210-092915 10.1084/jem.180.4.1345 10.4049/jimmunol.173.12.7190 10.1016/S1074-7613(02)00427-2 10.1002/eji.1830260429 |
| ContentType | Journal Article |
| Copyright | 2021 The Authors. published by Wiley‐VCH GmbH 2021 The Authors. European Journal of Immunology published by Wiley-VCH GmbH. 2021. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| Copyright_xml | – notice: 2021 The Authors. published by Wiley‐VCH GmbH – notice: 2021 The Authors. European Journal of Immunology published by Wiley-VCH GmbH. – notice: 2021. This article is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. |
| DBID | 24P AAYXX CITATION NPM 7QP 7T5 7TK 7TM 8FD FR3 H94 K9. M7N P64 RC3 7X8 |
| DOI | 10.1002/eji.202048974 |
| DatabaseName | Wiley Online Library Open Access CrossRef PubMed Calcium & Calcified Tissue Abstracts Immunology Abstracts Neurosciences Abstracts Nucleic Acids Abstracts Technology Research Database Engineering Research Database AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Algology Mycology and Protozoology Abstracts (Microbiology C) Biotechnology and BioEngineering Abstracts Genetics Abstracts MEDLINE - Academic |
| DatabaseTitle | CrossRef PubMed Genetics Abstracts Technology Research Database Algology Mycology and Protozoology Abstracts (Microbiology C) Nucleic Acids Abstracts AIDS and Cancer Research Abstracts ProQuest Health & Medical Complete (Alumni) Immunology Abstracts Engineering Research Database Calcium & Calcified Tissue Abstracts Neurosciences Abstracts Biotechnology and BioEngineering Abstracts MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic PubMed Genetics Abstracts |
| Database_xml | – sequence: 1 dbid: 24P name: Wiley Online Library Open Access url: https://authorservices.wiley.com/open-science/open-access/browse-journals.html sourceTypes: Publisher – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine Biology |
| EISSN | 1521-4141 |
| EndPage | 1545 |
| ExternalDocumentID | 33559929 10_1002_eji_202048974 EJI4997 |
| Genre | letter Letter Commentary Editorial |
| GrantInformation_xml | – fundername: Stiftelsen Kristian Gerhard Jebsen funderid: SKGJ‐MED‐017 – fundername: Helse Sør‐Øst RHF funderid: 2011050; 2018068 – fundername: Helse Sør-Øst RHF grantid: 2011050 – fundername: Stiftelsen Kristian Gerhard Jebsen grantid: SKGJ-MED-017 – fundername: Helse Sør-Øst RHF grantid: 2018068 |
| GroupedDBID | --- .3N .55 .GA .GJ .HR .Y3 05W 0R~ 10A 1L6 1OB 1OC 1ZS 24P 31~ 33P 3O- 3SF 3WU 4.4 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 53G 5GY 5RE 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHHS AAHQN AAIPD AAMNL AANHP AANLZ AAONW AASGY AAXRX AAYCA AAZKR ABCQN ABCUV ABEFU ABEML ABIJN ABJNI ABLJU ABPVW ABQWH ACAHQ ACBWZ ACCFJ ACCZN ACFBH ACGFS ACPOU ACPRK ACRPL ACSCC ACXBN ACXQS ACYXJ ADBBV ADEOM ADIZJ ADKYN ADMGS ADNMO ADOZA ADXAS ADZMN ADZOD AEEZP AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFFNX AFFPM AFGKR AFPWT AFRAH AFWVQ AFZJQ AHBTC AHMBA AI. AITYG AIURR AIWBW AJBDE AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN ALVPJ AMBMR AMYDB AOETA ASPBG ATUGU AUFTA AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BMNLL BMXJE BNHUX BROTX BRXPI BY8 CS3 D-E D-F DCZOG DPXWK DR2 DRFUL DRSTM DU5 EBD EBS EJD EMOBN F00 F01 F04 F5P FEDTE G-S G.N GNP GODZA H.T H.X HBH HF~ HGLYW HHY HHZ HVGLF HZ~ IX1 J0M J5H JPC KQQ L7B LATKE LAW LC2 LC3 LEEKS LH4 LITHE LOXES LP6 LP7 LUTES LW6 LYRES M65 MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NF~ NNB O66 O9- OHT OIG OK1 OVD P2P P2W P2X P4D PALCI PQQKQ Q.N Q11 QB0 QRW R.K RGB RIWAO RJQFR ROL RWI RX1 SAMSI SUPJJ SV3 TEORI UB1 UPT V2E VH1 W8V W99 WBKPD WHWMO WIB WIH WIK WIN WJL WOHZO WQJ WRC WUP WVDHM WXSBR X7M XG1 XPP XV2 Y6R ZGI ZXP ZZTAW ~IA ~KM ~WT AAYXX AEYWJ AGHNM AGQPQ AGYGG CITATION NPM 7QP 7T5 7TK 7TM 8FD AAMMB AEFGJ AGXDD AIDQK AIDYY FR3 H94 K9. M7N P64 RC3 7X8 |
| ID | FETCH-LOGICAL-c4037-60f3bda8b3da1f9a243e74dc7794bfb3392c326effd24190f77247f47a0c1b953 |
| IEDL.DBID | DR2 |
| ISSN | 0014-2980 1521-4141 |
| IngestDate | Fri Jul 11 06:38:35 EDT 2025 Fri Jul 25 10:01:26 EDT 2025 Thu Apr 03 07:05:41 EDT 2025 Tue Jul 01 03:51:30 EDT 2025 Thu Apr 24 23:08:14 EDT 2025 Wed Jan 22 16:28:35 EST 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | celiac disease single cell sequencing TCR CD8+ αβ T cells intraepithelial lymphocytes |
| Language | English |
| License | Attribution 2021 The Authors. European Journal of Immunology published by Wiley-VCH GmbH. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c4037-60f3bda8b3da1f9a243e74dc7794bfb3392c326effd24190f77247f47a0c1b953 |
| Notes | The authors contributed equally to this work SourceType-Scholarly Journals-1 content type line 14 ObjectType-Editorial-2 ObjectType-Commentary-1 ObjectType-Article-2 ObjectType-Correspondence-1 content type line 23 |
| ORCID | 0000-0001-8860-704X |
| OpenAccessLink | https://proxy.k.utb.cz/login?url=https://onlinelibrary.wiley.com/doi/abs/10.1002%2Feji.202048974 |
| PMID | 33559929 |
| PQID | 2537418506 |
| PQPubID | 986365 |
| PageCount | 4 |
| ParticipantIDs | proquest_miscellaneous_2487749739 proquest_journals_2537418506 pubmed_primary_33559929 crossref_citationtrail_10_1002_eji_202048974 crossref_primary_10_1002_eji_202048974 wiley_primary_10_1002_eji_202048974_EJI4997 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | June 2021 |
| PublicationDateYYYYMMDD | 2021-06-01 |
| PublicationDate_xml | – month: 06 year: 2021 text: June 2021 |
| PublicationDecade | 2020 |
| PublicationPlace | Germany |
| PublicationPlace_xml | – name: Germany – name: Weinheim |
| PublicationTitle | European journal of immunology |
| PublicationTitleAlternate | Eur J Immunol |
| PublicationYear | 2021 |
| Publisher | Wiley Subscription Services, Inc |
| Publisher_xml | – name: Wiley Subscription Services, Inc |
| References | 1991; 253 2002; 17 2017; 198 2011; 29 1994; 180 1996; 26 2004; 173 2004; 34 e_1_2_6_9_1 e_1_2_6_8_1 e_1_2_6_5_1 e_1_2_6_4_1 e_1_2_6_10_1 e_1_2_6_7_1 e_1_2_6_6_1 e_1_2_6_3_1 e_1_2_6_2_1 |
| References_xml | – volume: 253 start-page: 1411 year: 1991 end-page: 1415 publication-title: Science – volume: 180 start-page: 1337 year: 1994 end-page: 1344 publication-title: J. Exp. Med. – volume: 198 start-page: 3005 year: 2017 end-page: 3014 publication-title: J. Immunol. – volume: 173 start-page: 7190 year: 2004 end-page: 7199 publication-title: J. Immunol. – volume: 34 start-page: 3389 year: 2004 end-page: 3400 publication-title: Eur. J. Immunol. – volume: 180 start-page: 1345 year: 1994 end-page: 1358 publication-title: J. Exp. Med. – volume: 17 start-page: 487 year: 2002 end-page: 499 publication-title: Immunity – volume: 26 start-page: 914 year: 1996 end-page: 921 publication-title: Eur. J. Immunol. – volume: 29 start-page: 493 year: 2011 end-page: 525 publication-title: Annu. Rev. Immunol. – ident: e_1_2_6_6_1 doi: 10.1002/eji.200425122 – ident: e_1_2_6_7_1 doi: 10.1126/science.1716785 – ident: e_1_2_6_3_1 doi: 10.4049/jimmunol.1601693 – ident: e_1_2_6_8_1 doi: 10.1084/jem.180.4.1337 – ident: e_1_2_6_2_1 doi: 10.1146/annurev-immunol-040210-092915 – ident: e_1_2_6_4_1 doi: 10.1084/jem.180.4.1345 – ident: e_1_2_6_9_1 doi: 10.4049/jimmunol.173.12.7190 – ident: e_1_2_6_10_1 doi: 10.1016/S1074-7613(02)00427-2 – ident: e_1_2_6_5_1 doi: 10.1002/eji.1830260429 |
| SSID | ssj0009659 |
| Score | 2.41026 |
| Snippet | We compared the αβ T‐cell receptor repertoires of CD8+ αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single‐cell... We compared the αβ T-cell receptor repertoires of CD8 αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single-cell... We compared the αβ T-cell receptor repertoires of CD8+ αβ intraepithelial lymphocytes from celiac disease patients and healthy subjects by single-cell... |
| SourceID | proquest pubmed crossref wiley |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 1542 |
| SubjectTerms | CD8 antigen CD8+ αβ T cells Celiac disease intraepithelial lymphocytes Lymphocytes T single cell sequencing T cell receptors TCR |
| Title | Single‐cell TCR repertoire analysis reveals highly polyclonal composition of human intraepithelial CD8+ αβ T lymphocytes in untreated celiac disease |
| URI | https://onlinelibrary.wiley.com/doi/abs/10.1002%2Feji.202048974 https://www.ncbi.nlm.nih.gov/pubmed/33559929 https://www.proquest.com/docview/2537418506 https://www.proquest.com/docview/2487749739 |
| Volume | 51 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3NbtQwELagEohLgQLtQqkGCXEpabO2s0mOaGlVKoFQ2Uq9BduxpUKUrLa7h3DiETjyGvAgfQiehBnHm2pBICHOGStOPD_f2ONvGHuKUUQg8M4iaUUZSWezSMclLggfCSWFFdz5Atk3o6NTeXyWnIU-p3QXpuOH6DfcyDK8vyYDV_pi_4o01H44x_SOeGcREqMPpnotAkUnV_RRRJbXeWIZ8TyLA8cmjt9fGb0ak34Dmqu41Qeew9vs_XLKXb3Jx73FXO-ZT7-wOf7HN91h6wGUwotOi-6ya7beYDe6NpXtBrv5OhzA32Nf32Goq-yPz19oxx8m4xOY2amdzRt0naACwwkQLxTqNRAZctXCtKlaUxHmByphD3Vi0DjwLQLhnHaY7ZSuh1RoDzB-me3C5bfL7zCBqkV9a0yLkBjlYFH70nhbgiFZA-GE6T47PTyYjI-i0NwhMtJfTYyd0KXKtCjV0OWKo2KksjQpOgjttEDcZhBaWudKBBl57DANkKmTqYrNUOeJeMDW6qa2WwwwKcK0KOFZnFiMyalGEGlR2YbGuNiM1IA9Xy5vYQLzOTXgqIqOs5kX-N-L_r8P2LNefNpRfvxJcHupK0Ww_IuCJ8ITAsWjAXvSP0abpWVRtW0WKINZYirzVOQDttnpWP8mIYgDjuOTXa8pf59CcXD8CnPW9OE_ST9itziV5vjNpG22Np8t7GPEVnO9w65z-XbHm9FPVa8fiw |
| linkProvider | Wiley-Blackwell |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3NbtQwEB5BEZQLP-VvocAgIS4lbTZ2NskRbVttS9tD2Uq9RY5jS6VRslp2D-HEI3DkNeBB-hA8CTNONmVBICHOniROPOP5ZjL-BuAleRFBwDv2pBG5J62JvczPaUGCgVBSGBFYVyB7NBidyP3T8PSnU_wNP0SXcGPLcPs1GzgnpLcuWUPN-zOK75h4ljDxVbjGXb2ZPX_7-JJAiunymr1YekES-y3LJt1ga-nyZa_0G9RcRq7O9ezeBrWYdFNxcr45n2Wb-uMvfI7_81Z34FaLS_FNo0h34Yop1-B606myXoMbh-0_-Hvw5R15u8J8__SZk_44Hh7j1EzMdFbR7omqJTlBpoYi1UbmQy5qnFRFrQuG_chV7G2pGFYWXZdAPOMks5nwCZGCTAKH2_EGXny9-IZjLGpSuUrXhIpJDuelq443OWqW1dj-ZLoPJ7s74-HIa_s7eFq604m-FVmu4kzkqm8TFZBuRDLXEe0Rmc0EQTdN6NJYmxPOSHxLkYCMrIyUr_tZEooHsFJWpXkESHERRUZhEPuhIbccZYQjDelbX2vr64HqwevF-qa6JT_nHhxF2tA2Byl997T77j141YlPGtaPPwmuL5QlbY3_QxqEwnEC-YMevOiGyWx5WVRpqjnJUKAYySQSSQ8eNkrWPUkIpoELaGTDqcrfp5Du7O9R2Bo9_ifp57A6Gh8epAd7R2-fwM2AK3VcbmkdVmbTuXlKUGuWPXPW9ANxDiLQ |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwlV3NbtRADLagiIoLggJloYCREJcSNTsz-TuibVdtgaqCrdRblExmpKIoiZbdQ248AkdeAx6kD8GTYE-mW60QSJzj_Ci2x589ns8AryiKSALeaaCMrAJlTRqUYUUKEbEslDRSWNcgexIfnqnj8-jczznlszADP8Sq4Mae4dZrdvCusnvXpKHm8wWld8w7S5D4JtziDT_u6RLq9Jp1N44G_DtWgcjS0JNs0gP21m5fD0p_IM114Ooiz_Qe3PWQEd8OOr4PN0yzBbeHIZL9Fmx-8NvjD-D7JwpEtfn19RvX43E2-Yhz05n5oqWFDQvPP4LM2kRWh0xVXPfYtXWva0bkyA3mvosLW4tugB9ecP3XdHx4oyZrxcl-uouXPy5_4gzrnqyh1T0BVpLDZeMa102FmmU1-v2fh3A2PZhNDgM_eiHQyh0cDK0sqyItZVWMbVYIUluiKp2Q-5a2lISqNAE_Y21FECALLYF0lViVFKEel1kkH8FG0zbmMSClLJS0RCINI0MRMykJ4hkyhbHWNtRxMYI3V_8-156XnMdj1PnAqCxyUlW-UtUIXq_Eu4GQ42-CO1eKzL1ffslFJB1dTxiP4OXqMnkUq6VoTLskGcrhEpUlMhvB9mAAqzdJyQxtgq7sOov49yfkB8dHlFEmT_5L-gVsnu5P8_dHJ--ewh3BPTSu6rMDG4v50jwjELQonztD_w1POAB- |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Single-cell+TCR+repertoire+analysis+reveals+highly+polyclonal+composition+of+human+intraepithelial+CD8%2B+%CE%B1%CE%B2+T+lymphocytes+in+untreated+celiac+disease&rft.jtitle=European+journal+of+immunology&rft.au=Eggesb%C3%B8%2C+Linn+M&rft.au=Risnes%2C+Louise+F&rft.au=Neumann%2C+Ralf+S&rft.au=Lundin%2C+Knut+E+A&rft.date=2021-06-01&rft.issn=1521-4141&rft.eissn=1521-4141&rft.volume=51&rft.issue=6&rft.spage=1542&rft_id=info:doi/10.1002%2Feji.202048974&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0014-2980&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0014-2980&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0014-2980&client=summon |