Comparison of human and canine external femoral morphologies in the context of total hip replacement

The canine is frequently used as a model for human hip arthroplasty research. In order to better understand the appropriateness of the canine as a model for human total hip replacement studies, the external morphology of canine and human femurs were examined and compared. Several differences were fo...

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Bibliographic Details
Published inJournal of biomedical materials research Vol. 27; no. 9; p. 1149
Main Authors Bloebaum, R D, Ota, D T, Skedros, J G, Mantas, J P
Format Journal Article
LanguageEnglish
Published United States 01.09.1993
Subjects
Adolescent
Adult
Aged
Aging - physiology
Animals
Biomechanical Phenomena
Dogs
Female
Femur - anatomy & histology
Femur Head - anatomy & histology
Hip Prosthesis
Humans
Male
Middle Aged
Species Specificity
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Summary:The canine is frequently used as a model for human hip arthroplasty research. In order to better understand the appropriateness of the canine as a model for human total hip replacement studies, the external morphology of canine and human femurs were examined and compared. Several differences were found between canine and human femora, including angular measurements, anterior bow, and femoral head position relative to the femoral diaphysis. In addition, the human femur was noted to undergo age-related changes in several of the measured parameters. The canine femur did not exhibit any age-related changes in the measured parameters. This study suggests that there are limitations to the use of the canine model in human hip arthroplasty research, and that discretion must be exercised when attempting to extrapolate results from a canine study to the human clinical condition.
ISSN:0021-9304
DOI:10.1002/jbm.820270905