Application of graphene-modified electrode for selective detection of dopamine

• Published in: Electrochemistry communications Vol. 11; no. 4; pp. 889 - 892
• Main Authors: Wang, Ying, Li, Yueming, Tang, Longhua, Lu, Jin, Li, Jinghong
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 01.04.2009; Amsterdam Elsevier; New York, NY
• Subjects: Bioelectrochemisty; Biological and medical sciences; Biosensors; Biotechnology; Chitosan; Dopamine; Fundamental and applied biological sciences. Psychology; Graphene; Methods. Procedures. Technologies; Selective detection; Various methods and equipments; Selective detection; Dopamine; Chitosan; Graphene; Bioelectrochemisty; Scanning electron microscopy; Ascorbic acid; Chemical analysis; Vitamin; Catecholamine; Carbon; X ray diffraction; Electrochemical detector; Surface structure; Electrodes; Cyclic voltammetry; Transmission electron microscopy; Biosensor; Morphology; Biogenic amine; Glassy state; Modified material
• ISSN: 1388-2481; 1873-1902
• DOI: 10.1016/j.elecom.2009.02.013

Graphene was synthesized chemically by Hummers and Offeman method and the graphene-modified electrode was applied in selective determination of dopamine with a linear range from 5 μM to 200 μM in a large excess of ascorbic acid. Selective detection was realized in completely eliminating ascorbic acid, different from the methods based on the potential separations. π–π stacking interaction between dopamine and graphene surface may accelerate the electron transfer whereas weaken the ascorbic acid oxidation on this graphene-modified electrode. The resulted graphene-modified electrode also showed a better performance than multi-walled carbon nanotubes-modified electrode. The phenomena were considered from the elusive two-dimensional structure and unique electronic properties of graphene.