The Influence of Nutrigenetics on the Lipid Profile: Interaction Between Genes and Dietary Habits
Nutrigenetics is a new field with few studies in Latin America. Our aim is to investigate the way in which different genes related to the lipid profile influence the response to specific dietary habits. Eight polymorphisms on seven genes were investigated in a sample ( n = 567) from Porto Alegre, R...
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Published in | Biochemical genetics Vol. 48; no. 3-4; pp. 342 - 355 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
Boston
Springer US
01.04.2010
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | Nutrigenetics is a new field with few studies in Latin America. Our aim is to investigate the way in which different genes related to the lipid profile influence the response to specific dietary habits. Eight polymorphisms on seven genes were investigated in a sample (
n
= 567) from Porto Alegre, RS, Brazil. All the volunteers completed a food diary that was then assessed and classified into nine food groups. A number of nutrigenetic interactions were detected primarily related to the apolipoprotein E (
apoE
) gene. For example, frequent consumption of foods rich in polyunsaturated fat resulted in the beneficial effect of increasing HDL-C only in individuals who were not carriers of the
E
*
4
allele of the
APOE
gene, whereas variations in eating habits of
E
*
4
carriers did not affect their HDL-C (
P
= 0.018). Our data demonstrate for the first time nutrigenetic interactions in a Brazilian population. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0006-2928 1573-4927 |
DOI: | 10.1007/s10528-010-9331-6 |