Antimicrobial and Osseointegration Properties of Nanostructured Titanium Orthopaedic Implants

The surface design of titanium implants influences not only the local biological reactions but also affects at least the clinical result in orthopaedic application. During the last decades, strong efforts have been made to improve osteointegration and prevent bacterial adhesion to these surfaces. Fo...

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Published inMaterials Vol. 10; no. 11; p. 1302
Main Authors Jäger, Marcus, Jennissen, Herbert P, Dittrich, Florian, Fischer, Alfons, Köhling, Hedda Luise
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 13.11.2017
MDPI
Subjects
Adhesive strength
antimicrobial
Bacteria
Biocompatibility
Biological effects
Biomedical materials
bone
Cascades
implants
Literature reviews
Loosening
Nanostructure
Nanotechnology
Orthopaedic implants
protein layer
Review
Surgical implants
Titanium
Transplants & implants
antimicrobial
nanostructure
bone
implants
protein layer
titanium
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Summary:The surface design of titanium implants influences not only the local biological reactions but also affects at least the clinical result in orthopaedic application. During the last decades, strong efforts have been made to improve osteointegration and prevent bacterial adhesion to these surfaces. Following the rule of "smaller, faster, cheaper", nanotechnology has encountered clinical application. It is evident that the hierarchical implant surface micro- and nanotopography orchestrate the biological cascades of early peri-implant endosseous healing or implant loosening. This review of the literature gives a brief overview of nanostructured titanium-base biomaterials designed to improve osteointegration and prevent from bacterial infection.
Bibliography:ObjectType-Article-2
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ObjectType-Review-1
ISSN:1996-1944
1996-1944
DOI:10.3390/ma10111302