An acrasin-like attractant from yeast extract specific for Dictyostelium lacteum

The transition of the unicellular to the multicellular stage in Dictyostelium lacteum is not mediated by cyclic AMP. The attractant for aggregative amoebae of this cellular slime mold species was isolated from yeast extract and purified more than 1000-fold without a significant loss of activity. Sev...

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Bibliographic Details
Published inDevelopmental biology Vol. 57; no. 2; pp. 450 - 453
Main Authors Mato, JoséM., van Haastert, Peter J.M., Krens, Frans A., Konijn, Theo M.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.06.1977
Subjects
Cell Aggregation - drug effects
Chemotaxis - drug effects
Dictyostelium - cytology
Dictyostelium - drug effects
Myxomycetes - drug effects
Saccharomyces cerevisiae - isolation & purification
Saccharomyces cerevisiae - physiology
Species Specificity
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Summary:The transition of the unicellular to the multicellular stage in Dictyostelium lacteum is not mediated by cyclic AMP. The attractant for aggregative amoebae of this cellular slime mold species was isolated from yeast extract and purified more than 1000-fold without a significant loss of activity. Several characteristics of the chemotactic molecule specific for D. lacteum are reported, and the presence of an inactivating enzyme has been demonstrated.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0012-1606
1095-564X
DOI:10.1016/0012-1606(77)90229-9