Nematicidal Constituents from the Essential Oil of Chenopodium Ambrosioides Aerial Parts

• Published in: E-journal of chemistry Vol. 8; no. S1; pp. S143 - S148
• Main Authors: Bai, Chuan Qi, Liu, Zhi Long, Liu, Qi Zhi
• Format: Journal Article
• Language: English
• Published: Hindawi Limited 2011
• ISSN: 2090-9063; 0973-4945; 2090-9071; 2090-9810
• DOI: 10.1155/2011/470862

Essential oil of Chinese medicinal herb, Chenopodium ambrosioides aerial parts was found to possess nematicidal activity against the root‐knot nematodes, Meloidogyne incognita . The essential oil of C. ambrosioides was obtained by hydrodistillation and analyzed by gas chromatography‐mass spectrometry (GC‐MS). A total of 27 components of the essential oil were identified. The principal compounds in C. ambrosioides essential oil were ( Z )‐ascaridole (27.27%), ρ ‐cymene (19.05%), isoascaridole (14.75%), α ‐pinene (6.33%) and α ‐terpinene (5.12%). Bioactivity‐guided chromatographic separation of the essential oil on repeated silica gel columns led to isolate three volatile components (( Z )‐ascaridole, ρ ‐cymene and isoascaridole) from the essential oil. The essential oil and ( Z )‐ascaridole exhibited strong nematicidal activity against M. incognita with LC 50 values of 49.55 μg/mL and 32.79 μg/mL, respectively. ρ ‐Cymene and isoascaridole also possessed nematicidal activity against M. incognita with LC 50 values of 435.89 μg/mL and 1323.51 μg/mL, respectively but weaker than the crude essential oil.