Optimized preparation of zinc-inorganic antibacterial material containing samarium using response surface methodology

• Published in: Journal of rare earths Vol. 32; no. 9; pp. 900 - 906
• Main Author: 毛翠萍 张彬 唐晓宁 李欢 何琼
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.09.2014
• Subjects: Analysis of variance; Antiinfectives and antibacterials; Design engineering; inorganic antibacterial material; Rare earth metals; rare earths; Reaction time; response surface; Response surface methodology; samarium; Stirring; Zinc; zinc ion; 优化; 制备; 反应时间; 响应曲面法; 搅拌速度; 无机抗菌材料; 钐; 锌; inorganic antibacterial material; samarium; zinc ion; response surface; rare earths
• ISSN: 1002-0721; 2509-4963
• DOI: 10.1016/S1002-0721(14)60161-7

A Box-Behnken design （BBD） of response surface methodology （RSM） was used to optimize the preparation of the Zn-Sm antibacterial white carbon black by the sol-gel method. The statistical analysis of the results showed that the particle size of the Zn-Sm antibacterial white carbon black was significantly affected by the reaction time, reaction temperature and the stirring speed. According to analysis of variance （ANOVA）, the values of the determination coefficient （R2=0.9821） and the ＂Pred R-Squared＂ of 0.8227 were in reasonable agreement with the ＂Adj R-Squared＂ of 0.9591. It was indicated that this model could be used to navigate the design space. The optimized reaction time, temperature and the stirring speed were 0.88 h, 87.83 ℃, and 473.45 r/rain, respectively. In addition, the bacteriostasis rate of the product was about 97.92%.