Embryotoxicity and Biotransformation Responses in Zebrafish Exposed to Water-Soluble Fraction of Crude Oil

• Published in: Bulletin of environmental contamination and toxicology Vol. 86; no. 4; pp. 389 - 393
• Main Authors: Pauka, Luciana M., Maceno, Marcell, Rossi, Stefani C., Silva de Assis, Helena C.
• Format: Journal Article
• Language: English
• Published: New York Springer-Verlag 01.04.2011; Springer Nature B.V
• Subjects: Abnormalities, Drug-Induced - embryology; Abnormalities, Drug-Induced - metabolism; Animals; Aquatic Pollution; Biotransformation; Crude oil; Cytochrome P-450 CYP1A1 - metabolism; Danio rerio; Dose-Response Relationship, Drug; Earth and Environmental Science; Ecotoxicology; Embryo, Nonmammalian - drug effects; Embryo, Nonmammalian - metabolism; Embryonic growth stage; Embryos; Environment; Environmental Chemistry; Environmental Health; Fish; Freshwater; Glutathione Transferase - metabolism; Petroleum - toxicity; Pigmentation; Pollution; Soil Science & Conservation; Toxicity; Waste Water Technology; Water; Water Management; Water Pollutants, Chemical - toxicity; Water Pollution Control; Zebrafish - embryology; Zebrafish - metabolism; ASW, Atlantic, Campos Basin; Embryotoxicity; Zebrafish; Crude oil; Biotransformation
• ISSN: 0007-4861; 1432-0800
• DOI: 10.1007/s00128-011-0235-x

The toxic effects of water-soluble fraction (WSF) of crude oil (API27, Petrobras Campos Basin, Brazil) were evaluated during the early life stages of zebrafish, as well as its biotransformation in juvenile fish. Embryonic development was studied during 96 h. Reduced heartbeat rate, weak pigmentation, tail defects, and embryo mortality were observed for all of the tested concentrations of the WSF. Activities of the biotransformation enzymes were induced at the highest concentrations, showing that these enzymes played a role in its elimination. As shown in this study the crude oil WSF altered the normal embryonic development of fish.