Circumdatin H, a new inhibitor of mitochondrial NADH oxidase, from Aspergillus ochraceus
Circumdatin H (1), a new alkaloid from the culture broth of Aspergillus ochraceus, has been isolated, together with a known circumdatin, circumdatin E (2) and other known compounds: flavacol (3) and stephacidin A (4). The structure of 1 was established on the basis of chemical and spectral evidence....
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| Published in | Journal of antibiotics Vol. 58; no. 6; pp. 416 - 419 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
TOKYO
Japan Antibiotics Research Assoc
01.06.2005
Nature Publishing Group |
| Subjects | |
| Online Access | Get full text |
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| Abstract | Circumdatin H (1), a new alkaloid from the culture broth of Aspergillus ochraceus, has been isolated, together with a known circumdatin, circumdatin E (2) and other known compounds: flavacol (3) and stephacidin A (4). The structure of 1 was established on the basis of chemical and spectral evidence. All of these alkaloids showed biological activity as inhibitors of the mammalian mitochondrial respiratory chain. |
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| AbstractList | Circumdatin H (1), a new alkaloid from the culture broth of Aspergillus ochraceus, has been isolated, together with a known circumdatin, circumdatin E (2) and other known compounds: flavacol (3) and stephacidin A (4). The structure of 1 was established on the basis of chemical and spectral evidence. All of these alkaloids showed biological activity as inhibitors of the mammalian mitochondrial respiratory chain. |
| Author | Estornell, E Primo, J Gonzalez, MC Moya, P Romero Lopez-Gresa, MP |
| Author_xml | – sequence: 1 givenname: MP surname: Lopez-Gresa fullname: Lopez-Gresa, MP email: mplopez@ceqa.upv.es – sequence: 2 givenname: MC surname: Gonzalez fullname: Gonzalez, MC – sequence: 3 givenname: J orcidid: 0000-0003-2254-8184 surname: Primo fullname: Primo, J – sequence: 4 givenname: P surname: Moya fullname: Moya, P – sequence: 5 surname: Romero fullname: Romero – sequence: 6 givenname: E surname: Estornell fullname: Estornell, E |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/16156520$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1021/jm0011373 10.1021/ja028538n 10.1002/ps.2780450405 10.7164/antibiotics.54.911 10.1111/j.1432-1033.1991.tb15945.x 10.1016/S0040-4020(01)93786-X 10.1016/S0005-2728(98)00034-6 10.1016/0014-5793(93)80498-J 10.1021/jo981536u 10.1248/cpb.20.2274 10.1021/np000381u 10.1021/np980495u 10.1021/bi9516034 10.1021/jf981188x 10.1016/S0005-2728(98)00030-9 |
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| Keywords | Aspergillus ochraceus flavacol stephacidin A RESPIRATORY-CHAIN ANALOGS COMPLEX I INHIBITORS alkaloids OXIDOREDUCTASE mitochondrial respiratory chain inhibitors circumdatin benzodiazepine |
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| References | Fang, NB (WOS:000080427200057) 1999; 47 Rahbaek, L (WOS:000079022600041) 1999; 64 Lummen, P (WOS:000073897100016) 1998; 1364 ESTORNELL, E (WOS:A1993MA77800029) 1993; 332 (WOS:000230261300008.3) 2001 Miyoshi, H (WOS:000073897100012) 1998; 1364 YAMAZAKI, M (WOS:A1972N911000033) 1972; 20 CUTRONE JQ (WOS:000230261300008.5) 2002; 124 Dai, JR (WOS:000166696400032) 2001; 64 WEISS, H (WOS:A1991FL85500001) 1991; 197 Rahbaek, L (WOS:000081140100025) 1999; 62 Fontana, A (WOS:000169625500012) 2001; 44 (WOS:000230261300008.2) 2000 (WOS:000230261300008.1) 1989 Fato, R (WOS:A1996TX50000025) 1996; 35 MACDONALD, JC (WOS:A1976BL42900002) 1976; 32 Balcells, M (WOS:A1995TK69400004) 1995; 45 Sugie, Y (WOS:000172470300007) 2001; 54 BFja200554_CR2 BFja200554_CR1 JQ Cutrone (BFja200554_CR3) 2002; 124 BFja200554_CR4 M Yamazaki (BFja200554_CR10) 1972; 20 M Balcells (BFja200554_CR5) 1995; 45 E Estornell (BFja200554_CR14) 1993; 332 JR Dai (BFja200554_CR9) 2001; 64 JC MacDonald (BFja200554_CR11) 1976; 32 Y Sugie (BFja200554_CR6) 2001; 54 N Fang (BFja200554_CR17) 1999; 47 P Lümmen (BFja200554_CR12) 1998; 1364 H Weiss (BFja200554_CR18) 1991; 197 H Miyoshi (BFja200554_CR13) 1998; 1364 L Rahbak (BFja200554_CR8) 1999; 62 L Rahbak (BFja200554_CR7) 1999; 64 A Fontana (BFja200554_CR16) 2001; 44 R Fato (BFja200554_CR15) 1996; 35 |
| References_xml | – volume: 54 start-page: 911 year: 2001 ident: WOS:000172470300007 article-title: A new antibiotic CJ-17,665 from Aspergillus ochraceus publication-title: JOURNAL OF ANTIBIOTICS contributor: fullname: Sugie, Y – volume: 47 start-page: 2130 year: 1999 ident: WOS:000080427200057 article-title: Cube resin insecticide: Identification and biological activity of 29 rotenoid constituents publication-title: JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY contributor: fullname: Fang, NB – volume: 1364 start-page: 287 year: 1998 ident: WOS:000073897100016 article-title: Complex I inhibitors as insecticides and acaricides publication-title: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS contributor: fullname: Lummen, P – volume: 197 start-page: 563 year: 1991 ident: WOS:A1991FL85500001 article-title: THE RESPIRATORY-CHAIN NADH DEHYDROGENASE (COMPLEX-I) OF MITOCHONDRIA publication-title: EUROPEAN JOURNAL OF BIOCHEMISTRY contributor: fullname: WEISS, H – volume: 332 start-page: 127 year: 1993 ident: WOS:A1993MA77800029 article-title: ASSAY CONDITIONS FOR THE MITOCHONDRIAL NADH - COENZYME-Q OXIDOREDUCTASE publication-title: FEBS LETTERS contributor: fullname: ESTORNELL, E – volume: 20 start-page: 2274 year: 1972 ident: WOS:A1972N911000033 article-title: ISOLATION OF A NEW TYPE OF PYRAZINE METABOLITE FROM ASPERGILLUS-OCHRACEUS WILH publication-title: CHEMICAL & PHARMACEUTICAL BULLETIN contributor: fullname: YAMAZAKI, M – volume: 64 start-page: 1689 year: 1999 ident: WOS:000079022600041 article-title: Circumdatin A, B, and C: Three new benzodiazepine alkaloids isolated from a culture of the fungus Aspergillus ochraceus publication-title: JOURNAL OF ORGANIC CHEMISTRY contributor: fullname: Rahbaek, L – volume: 32 start-page: 655 year: 1976 ident: WOS:A1976BL42900002 article-title: C-13 AND PROTON NMR-SPECTRA OF 2(H-1)PYRAZINONES publication-title: TETRAHEDRON contributor: fullname: MACDONALD, JC – volume: 62 start-page: 904 year: 1999 ident: WOS:000081140100025 article-title: Circumdatins D, E, and F: Further fungal benzodiazepine analogues from Aspergillus ochraceus publication-title: JOURNAL OF NATURAL PRODUCTS contributor: fullname: Rahbaek, L – volume: 35 start-page: 2705 year: 1996 ident: WOS:A1996TX50000025 article-title: Steady-state kinetics of the reduction of coenzyme Q analogs by complex I (NADH:Ubiquinone oxidoreductase) in bovine heart mitochondria and submitochondrial particles publication-title: BIOCHEMISTRY contributor: fullname: Fato, R – year: 2000 ident: WOS:000230261300008.2 – volume: 124 start-page: 14556 year: 2002 ident: WOS:000230261300008.5 publication-title: J AM CHEM SOC contributor: fullname: CUTRONE JQ – volume: 64 start-page: 125 year: 2001 ident: WOS:000166696400032 article-title: Circumdatin G, a new alkaloid from the fungus Aspergillus ochraceus publication-title: JOURNAL OF NATURAL PRODUCTS contributor: fullname: Dai, JR – volume: 45 start-page: 319 year: 1995 ident: WOS:A1995TK69400004 article-title: Effect of fungal metabolites and some derivatives against Tribolium castaneum (Herbst) and Nezara viridula (L) publication-title: PESTICIDE SCIENCE contributor: fullname: Balcells, M – volume: 1364 start-page: 236 year: 1998 ident: WOS:000073897100012 article-title: Structure-activity relationships of some complex I inhibitors publication-title: BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS contributor: fullname: Miyoshi, H – year: 1989 ident: WOS:000230261300008.1 – volume: 44 start-page: 2362 year: 2001 ident: WOS:000169625500012 article-title: Novel inhibitors of mitochondrial respiratory chain: Endoperoxides from the marine tunicate Stolonica socialis publication-title: JOURNAL OF MEDICINAL CHEMISTRY doi: 10.1021/jm0011373 contributor: fullname: Fontana, A – year: 2001 ident: WOS:000230261300008.3 – volume: 44 start-page: 2362 year: 2001 ident: BFja200554_CR16 publication-title: J Med Chem doi: 10.1021/jm0011373 contributor: fullname: A Fontana – volume: 124 start-page: 14556 year: 2002 ident: BFja200554_CR3 publication-title: J Am Chem Soc doi: 10.1021/ja028538n contributor: fullname: JQ Cutrone – volume: 45 start-page: 319 year: 1995 ident: BFja200554_CR5 publication-title: Pestic Sci doi: 10.1002/ps.2780450405 contributor: fullname: M Balcells – volume: 54 start-page: 911 year: 2001 ident: BFja200554_CR6 publication-title: J Antibiot doi: 10.7164/antibiotics.54.911 contributor: fullname: Y Sugie – volume: 197 start-page: 563 year: 1991 ident: BFja200554_CR18 publication-title: Eur J Biochem doi: 10.1111/j.1432-1033.1991.tb15945.x contributor: fullname: H Weiss – volume: 32 start-page: 655 year: 1976 ident: BFja200554_CR11 publication-title: Tetrahedron doi: 10.1016/S0040-4020(01)93786-X contributor: fullname: JC MacDonald – volume: 1364 start-page: 287 year: 1998 ident: BFja200554_CR12 publication-title: Biochim Biophys Acta doi: 10.1016/S0005-2728(98)00034-6 contributor: fullname: P Lümmen – ident: BFja200554_CR2 – ident: BFja200554_CR1 – volume: 332 start-page: 127 year: 1993 ident: BFja200554_CR14 publication-title: FEBS Lett doi: 10.1016/0014-5793(93)80498-J contributor: fullname: E Estornell – ident: BFja200554_CR4 – volume: 64 start-page: 1689 year: 1999 ident: BFja200554_CR7 publication-title: J Org Chem doi: 10.1021/jo981536u contributor: fullname: L Rahbak – volume: 20 start-page: 2274 year: 1972 ident: BFja200554_CR10 publication-title: Chem Pharm Bull doi: 10.1248/cpb.20.2274 contributor: fullname: M Yamazaki – volume: 64 start-page: 125 year: 2001 ident: BFja200554_CR9 publication-title: J Nat Prod doi: 10.1021/np000381u contributor: fullname: JR Dai – volume: 62 start-page: 904 year: 1999 ident: BFja200554_CR8 publication-title: J Nat Prod doi: 10.1021/np980495u contributor: fullname: L Rahbak – volume: 35 start-page: 2705 year: 1996 ident: BFja200554_CR15 publication-title: Biochemistry doi: 10.1021/bi9516034 contributor: fullname: R Fato – volume: 47 start-page: 2130 year: 1999 ident: BFja200554_CR17 publication-title: J Agric Food Chem doi: 10.1021/jf981188x contributor: fullname: N Fang – volume: 1364 start-page: 236 year: 1998 ident: BFja200554_CR13 publication-title: Biochim Biophys Acta doi: 10.1016/S0005-2728(98)00030-9 contributor: fullname: H Miyoshi |
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| SubjectTerms | Aspergillus ochraceus - metabolism Benzodiazepinones - isolation & purification Benzodiazepinones - pharmacology Biotechnology & Applied Microbiology Chemical Phenomena Chemistry, Physical Electron Transport - drug effects Enzyme Inhibitors - isolation & purification Enzyme Inhibitors - pharmacology Fermentation Immunology Life Sciences & Biomedicine Magnetic Resonance Spectroscopy Mass Spectrometry Microbiology Mitochondria - drug effects Mitochondria - enzymology Multienzyme Complexes - antagonists & inhibitors NADH, NADPH Oxidoreductases - antagonists & inhibitors Pharmacology & Pharmacy Science & Technology Spectrophotometry, Infrared Spectrophotometry, Ultraviolet |
| Title | Circumdatin H, a new inhibitor of mitochondrial NADH oxidase, from Aspergillus ochraceus |
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