Polysaccharides purified from Cordyceps cicadae protects PC12 cells against glutamate-induced oxidative damage

•Two polysaccharides CPA-1 and CPB-2 were purified from Cordyceps cicadae.•CPA-1 and CPB-2 protected PC12 cells from glutamate induced toxicity by increasing cell survival rate, decreasing the accumulation of ROS and Ca2+.•CPA-1 and CPB-2 increased GSH-Px and SOD activites. Two polysaccharides CPA-1...

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Published inCarbohydrate polymers Vol. 153; pp. 187 - 195
Main Authors Olatunji, Opeyemi J., Feng, Yan, Olatunji, Oyenike O., Tang, Jian, Wei, Yuan, Ouyang, Zhen, Su, Zhaoliang
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 20.11.2016
Subjects
Cordyceps cicadae
Glutamate
Neuroprotection
PC12 cells
Polysaccharide
Neuroprotection
Glutamate
Polysaccharide
PC12 cells
Cordyceps cicadae
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Abstract •Two polysaccharides CPA-1 and CPB-2 were purified from Cordyceps cicadae.•CPA-1 and CPB-2 protected PC12 cells from glutamate induced toxicity by increasing cell survival rate, decreasing the accumulation of ROS and Ca2+.•CPA-1 and CPB-2 increased GSH-Px and SOD activites. Two polysaccharides CPA-1 and CPB-2 were isolated purified from Cordyceps cicadae by hot water extraction, ethanol precipitation and purification using anion exchange and gel filtration chromatography. Preliminary structural characterization of CPA-1 and CPB-2 were performed. The protective effect of CPA-1 and CPB-2 against glutamate-induced oxidative toxicity in PC12 cells was analyzed. The results indicated that pretreatment of PC12 cells with CPA-1 and CPB-2 significantly increased cell survival, Ca2+ overload and ROS generation. CPA-1 and CPB-2 also markedly up-regulated the antioxidant status of pretreated PC12 cells. Our results suggested that Cordyceps cicadae polysaccharides can protect PC12 cells against glutamate excitotoxicity and might serve as therapeutic agents for neuronal disorders.
AbstractList •Two polysaccharides CPA-1 and CPB-2 were purified from Cordyceps cicadae.•CPA-1 and CPB-2 protected PC12 cells from glutamate induced toxicity by increasing cell survival rate, decreasing the accumulation of ROS and Ca2+.•CPA-1 and CPB-2 increased GSH-Px and SOD activites. Two polysaccharides CPA-1 and CPB-2 were isolated purified from Cordyceps cicadae by hot water extraction, ethanol precipitation and purification using anion exchange and gel filtration chromatography. Preliminary structural characterization of CPA-1 and CPB-2 were performed. The protective effect of CPA-1 and CPB-2 against glutamate-induced oxidative toxicity in PC12 cells was analyzed. The results indicated that pretreatment of PC12 cells with CPA-1 and CPB-2 significantly increased cell survival, Ca2+ overload and ROS generation. CPA-1 and CPB-2 also markedly up-regulated the antioxidant status of pretreated PC12 cells. Our results suggested that Cordyceps cicadae polysaccharides can protect PC12 cells against glutamate excitotoxicity and might serve as therapeutic agents for neuronal disorders.
Two polysaccharides CPA-1 and CPB-2 were isolated purified from Cordyceps cicadae by hot water extraction, ethanol precipitation and purification using anion exchange and gel filtration chromatography. Preliminary structural characterization of CPA-1 and CPB-2 were performed. The protective effect of CPA-1 and CPB-2 against glutamate-induced oxidative toxicity in PC12 cells was analyzed. The results indicated that pretreatment of PC12 cells with CPA-1 and CPB-2 significantly increased cell survival, Ca(2+) overload and ROS generation. CPA-1 and CPB-2 also markedly up-regulated the antioxidant status of pretreated PC12 cells. Our results suggested that Cordyceps cicadae polysaccharides can protect PC12 cells against glutamate excitotoxicity and might serve as therapeutic agents for neuronal disorders.
Author Olatunji, Oyenike O.
Ouyang, Zhen
Su, Zhaoliang
Wei, Yuan
Feng, Yan
Tang, Jian
Olatunji, Opeyemi J.
Author_xml – sequence: 1
  givenname: Opeyemi J.
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  givenname: Yan
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  organization: School of Pharmacy, Jiangsu University, Zhenjiang, 212013, China
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  givenname: Oyenike O.
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  surname: Tang
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  givenname: Zhaoliang
  surname: Su
  fullname: Su, Zhaoliang
  organization: School of Medical Science and Laboratory Medicine, Jiangsu University, Zhenjiang, 212013, China
BackLink https://www.ncbi.nlm.nih.gov/pubmed/27561486$$D View this record in MEDLINE/PubMed
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Cites_doi 10.1016/S0024-3205(03)00652-0
10.1371/journal.pone.0087578
10.1139/y2012-003
10.1523/JNEUROSCI.21-19-07455.2001
10.1523/JNEUROSCI.12-05-01882.1992
10.1021/bi020583k
10.1002/ptr.3320
10.1007/s12264-010-0813-7
10.1016/j.bbrc.2016.01.035
10.1089/jmf.2011.1575
10.1016/j.ejphar.2013.12.014
10.1016/S0891-5849(97)00020-8
10.1016/j.carbpol.2005.04.020
10.4049/jimmunol.156.9.3418
10.1006/jcis.2002.8681
10.1016/j.fct.2012.10.058
10.1021/jf020074p
10.1016/j.fct.2012.05.051
10.1016/j.fct.2012.04.022
10.1523/JNEUROSCI.10-01-00283.1990
10.1016/j.pbb.2011.11.002
10.1016/j.neuroscience.2008.03.007
10.1016/j.carbpol.2014.12.032
10.1016/j.carbpol.2009.04.017
10.1016/j.ijbiomac.2012.09.002
10.1007/s10072-010-0245-1
10.1038/35040009
10.1016/j.jep.2009.04.010
10.1006/bbrc.1995.2647
10.1016/j.ijbiomac.2015.01.010
10.1016/S0168-0102(00)00124-3
10.1016/j.fitote.2004.04.003
10.1046/j.1471-4159.2000.0741605.x
10.1016/j.carbpol.2012.07.026
10.1016/S0271-5317(96)00218-7
10.1124/mol.104.001081
10.1056/NEJM199403033300907
10.1007/s11274-012-1005-6
10.1016/j.fct.2011.02.008
10.2174/157015909787602823
10.1111/j.1471-4159.2006.03907.x
10.1016/j.neuint.2013.10.018
10.1100/tsw.2002.74
10.1016/j.ijbiomac.2014.05.049
10.1016/j.neuint.2009.12.020
10.2174/187152710791292567
10.1007/s00726-001-0120-8
10.1016/j.carbpol.2013.02.035
10.1016/j.brainres.2005.07.032
10.1016/j.jep.2010.11.063
10.1016/j.jep.2006.12.015
10.1016/j.tifs.2006.07.013
10.1016/S0300-9084(02)00039-1
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Keywords Neuroprotection
Glutamate
Polysaccharide
PC12 cells
Cordyceps cicadae
Language English
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References Ren, He, Cheng, Chang (bib0180) 2014; 9
Lipton, Rosenberg (bib0120) 1994; 330
Tzschentke (bib0235) 2002; 23
Rashid, Unyayar, Mazmanci, McKeown, Banat, Worthington (bib0175) 2011; 49
Penugonda, Mare, Goldstein, Banks, Ercal (bib0155) 2005; 1056
Pereira, Oliveira (bib0160) 1997; 23
Tang, Eisenbrand (bib0225) 1992
Ko, Lee, Samarakoon, Kim, Jeon (bib0090) 2013; 52
Cui, Cui, Wang, Song, Liang, Ji (bib0035) 2016; 470
Fisher, Yang (bib0045) 2002; 22
Li, Zhao, Ji, Dong, Lo, Cheung (bib0115) 2003; 73
Tokarski, Bobula, Wabno, Hess (bib0230) 2008; 153
Muller, Rice, Ensley, Coogan, Kalbfleish, Kelley (bib0140) 1996; 156
Sun, Mao, Chen, Guo, Li, Qi (bib0210) 2009; 78
Cheung, Li, Cheung, Zhu, Zheng, Bi (bib0025) 2009; 124
Sun, Zhang, Zhu, Chen, Mei (bib0215) 2010; 26
Mattson (bib0125) 2000; 1
Zhang, Wang, Jin, Zhang (bib0270) 2013; 95
Surendran, Rajasankar (bib0220) 2010; 31
Zhang, Lv, Pan, Pandey, He, Fan (bib0265) 2012; 51
Wu, Yan, Ma, Jia, Zhang, Guo (bib0250) 2012; 28
Jia, Rao, Xue, Lei (bib0065) 2015; 22
Zhao, Kan, Li, Chen (bib0275) 2005; 61
Pereira, Oliveira (bib0165) 2000; 37
Cheung (bib0020) 1996; 16
Li, Huang, Fua, Yue, Liu, You (bib0105) 2015; 75
Soto-Otero, Méndez-Alvarez, Hermida-Ameijeiras, Muñoz-Patiño, Labandeira-Garcia (bib0205) 2000; 74
Kawakami, Kanno, Ikarashi, Kase (bib0075) 2011; 134
Ko, Kim, Jeon (bib0095) 2012; 50
Baptisite, Hartwick, Jollimore, Baldridge, Seigel, Kelly (bib0010) 2004; 66
Li, Liu, Dluzen, Jin (bib0110) 2007; 111
Santhiya, Subramanian, Natarajan (bib0185) 2002; 256
Park, Yang, Yoon, Lee, Yang, Park (bib0150) 2002; 84
Kim, Kim, Ryu, Shin, Kang, Kim (bib0085) 2011; 14
Oster, Radad, Scheller, Hesse, Balanzew, Reichmann (bib0145) 2014; 724
Coimbra, Goncalves, Barros, Delgadillo (bib0030) 2002; 50
Schubert, Piasecki (bib0190) 2001; 21
Shen, Song, Wu, Zhang (bib0195) 2011; 25
Uttara, Singh, Zamboni, Mahajan (bib0240) 2009; 7
Gondim, Costa, Rocha, Brito, Ribeiro, Vale (bib0050) 2012; 904
Vazhappilly, Wee, Sucher, Low (bib0245) 2010; 56
Kim, Kim, Lee, Ryu, Kim, Yoon (bib0080) 2012; 50
Randall, Thayer (bib0170) 1992; 12
Han, Zhu, Wang, Chen, Li, Yao (bib0060) 2014; 64
Jin, Horning, Mayer, Gouaux (bib0070) 2002; 41
Zhang, Cui, Cheung, Wang (bib0260) 2007; 18
Kuo, Lin, Don, Liao, Tsai, Lee (bib0100) 2002; 13
Zong, Cao, Wang (bib0280) 2012; 90
Halliwell (bib0055) 2006; 97
Yu, Song, Zhao, Bin, Wang, Zhang (bib0255) 2004; 75
Albrecht, Lewerenz, Dittmer, Noack, Maher, Methner (bib0005) 2010; 9
Michaels, Rothman (bib0130) 1990; 10
Deng, Yang (bib0040) 2014; 69
Behl, Widmann, Trapp, Holsboer (bib0015) 1995; 216
Molnar, Saac (bib0135) 2002; 2
Siegel, Sanacora (bib0200) 2012; 100
Deng (10.1016/j.carbpol.2016.06.108_bib0040) 2014; 69
Surendran (10.1016/j.carbpol.2016.06.108_bib0220) 2010; 31
Ren (10.1016/j.carbpol.2016.06.108_bib0180) 2014; 9
Halliwell (10.1016/j.carbpol.2016.06.108_bib0055) 2006; 97
Sun (10.1016/j.carbpol.2016.06.108_bib0215) 2010; 26
Yu (10.1016/j.carbpol.2016.06.108_bib0255) 2004; 75
Oster (10.1016/j.carbpol.2016.06.108_bib0145) 2014; 724
Vazhappilly (10.1016/j.carbpol.2016.06.108_bib0245) 2010; 56
Pereira (10.1016/j.carbpol.2016.06.108_bib0165) 2000; 37
Penugonda (10.1016/j.carbpol.2016.06.108_bib0155) 2005; 1056
Zhang (10.1016/j.carbpol.2016.06.108_bib0270) 2013; 95
Li (10.1016/j.carbpol.2016.06.108_bib0110) 2007; 111
Park (10.1016/j.carbpol.2016.06.108_bib0150) 2002; 84
Rashid (10.1016/j.carbpol.2016.06.108_bib0175) 2011; 49
Siegel (10.1016/j.carbpol.2016.06.108_bib0200) 2012; 100
Cui (10.1016/j.carbpol.2016.06.108_bib0035) 2016; 470
Han (10.1016/j.carbpol.2016.06.108_bib0060) 2014; 64
Muller (10.1016/j.carbpol.2016.06.108_bib0140) 1996; 156
Baptisite (10.1016/j.carbpol.2016.06.108_bib0010) 2004; 66
Ko (10.1016/j.carbpol.2016.06.108_bib0090) 2013; 52
Zong (10.1016/j.carbpol.2016.06.108_bib0280) 2012; 90
Molnar (10.1016/j.carbpol.2016.06.108_bib0135) 2002; 2
Kawakami (10.1016/j.carbpol.2016.06.108_bib0075) 2011; 134
Schubert (10.1016/j.carbpol.2016.06.108_bib0190) 2001; 21
Sun (10.1016/j.carbpol.2016.06.108_bib0210) 2009; 78
Gondim (10.1016/j.carbpol.2016.06.108_bib0050) 2012; 904
Pereira (10.1016/j.carbpol.2016.06.108_bib0160) 1997; 23
Zhang (10.1016/j.carbpol.2016.06.108_bib0265) 2012; 51
Kim (10.1016/j.carbpol.2016.06.108_bib0080) 2012; 50
Cheung (10.1016/j.carbpol.2016.06.108_bib0020) 1996; 16
Fisher (10.1016/j.carbpol.2016.06.108_bib0045) 2002; 22
Randall (10.1016/j.carbpol.2016.06.108_bib0170) 1992; 12
Albrecht (10.1016/j.carbpol.2016.06.108_bib0005) 2010; 9
Cheung (10.1016/j.carbpol.2016.06.108_bib0025) 2009; 124
Jin (10.1016/j.carbpol.2016.06.108_bib0070) 2002; 41
Tzschentke (10.1016/j.carbpol.2016.06.108_bib0235) 2002; 23
Li (10.1016/j.carbpol.2016.06.108_bib0105) 2015; 75
Tokarski (10.1016/j.carbpol.2016.06.108_bib0230) 2008; 153
Shen (10.1016/j.carbpol.2016.06.108_bib0195) 2011; 25
Coimbra (10.1016/j.carbpol.2016.06.108_bib0030) 2002; 50
Ko (10.1016/j.carbpol.2016.06.108_bib0095) 2012; 50
Lipton (10.1016/j.carbpol.2016.06.108_bib0120) 1994; 330
Zhao (10.1016/j.carbpol.2016.06.108_bib0275) 2005; 61
Wu (10.1016/j.carbpol.2016.06.108_bib0250) 2012; 28
Behl (10.1016/j.carbpol.2016.06.108_bib0015) 1995; 216
Soto-Otero (10.1016/j.carbpol.2016.06.108_bib0205) 2000; 74
Tang (10.1016/j.carbpol.2016.06.108_bib0225) 1992
Kim (10.1016/j.carbpol.2016.06.108_bib0085) 2011; 14
Kuo (10.1016/j.carbpol.2016.06.108_bib0100) 2002; 13
Santhiya (10.1016/j.carbpol.2016.06.108_bib0185) 2002; 256
Jia (10.1016/j.carbpol.2016.06.108_bib0065) 2015; 22
Michaels (10.1016/j.carbpol.2016.06.108_bib0130) 1990; 10
Li (10.1016/j.carbpol.2016.06.108_bib0115) 2003; 73
Zhang (10.1016/j.carbpol.2016.06.108_bib0260) 2007; 18
Mattson (10.1016/j.carbpol.2016.06.108_bib0125) 2000; 1
Uttara (10.1016/j.carbpol.2016.06.108_bib0240) 2009; 7
References_xml – volume: 22
  start-page: 1737
  year: 2002
  end-page: 1754
  ident: bib0045
  article-title: Anticancer effects and mechanism of polysaccharide-K (PSK): implications of cancer immunotherapy
  publication-title: Anticancer Research
  contributor:
    fullname: Yang
– volume: 1
  start-page: 120
  year: 2000
  end-page: 129
  ident: bib0125
  article-title: Apoptosis in neurodegenerative disorders
  publication-title: Nature Reviews Molecular Cell Biology
  contributor:
    fullname: Mattson
– volume: 31
  start-page: 531
  year: 2010
  end-page: 540
  ident: bib0220
  article-title: Parkinson’s disease: oxidative stress and therapeutic approaches
  publication-title: Neurological Sciences
  contributor:
    fullname: Rajasankar
– volume: 13
  start-page: 209
  year: 2002
  end-page: 219
  ident: bib0100
  article-title: Cyclodepsipeptide and dioxomorpholine derivatives isolated from the insect-body portion of the fungus
  publication-title: Journal of Chinese Medicine
  contributor:
    fullname: Lee
– volume: 56
  start-page: 569
  year: 2010
  end-page: 576
  ident: bib0245
  article-title: A non-muscle myosin II motor links NR1 to retrograde trafficking and proteasomal degradation in PC12 cells
  publication-title: Neurochemistry International
  contributor:
    fullname: Low
– volume: 111
  start-page: 458
  year: 2007
  end-page: 463
  ident: bib0110
  article-title: Protective effects of ginsenoside Rg2 against glutamate-induced neurotoxicity in PC12 cells
  publication-title: Journal of Ethnopharmacology
  contributor:
    fullname: Jin
– volume: 50
  start-page: 2294
  year: 2012
  end-page: 2302
  ident: bib0095
  article-title: Protective effect of a novel antioxidant peptide purified from a marine
  publication-title: Food and Chemical Toxicology
  contributor:
    fullname: Jeon
– volume: 1056
  start-page: 132
  year: 2005
  end-page: 138
  ident: bib0155
  article-title: Effects of
  publication-title: Brain Research
  contributor:
    fullname: Ercal
– volume: 21
  start-page: 7455
  year: 2001
  end-page: 7462
  ident: bib0190
  article-title: Oxidative glutamate toxicity can be a component of the excitotoxicity cascade
  publication-title: Journal of Neuroscience
  contributor:
    fullname: Piasecki
– volume: 18
  start-page: 4
  year: 2007
  end-page: 19
  ident: bib0260
  article-title: Antitumor polysaccharides from mushrooms: a review on their isolation process: structural characteristics and antitumor activity
  publication-title: Trends in Food Science & Technology
  contributor:
    fullname: Wang
– volume: 330
  start-page: 613
  year: 1994
  end-page: 622
  ident: bib0120
  article-title: Excitatory amino acids as a final common pathway for neurologic disorders
  publication-title: New England Journal of Medicine
  contributor:
    fullname: Rosenberg
– volume: 100
  start-page: 653
  year: 2012
  end-page: 655
  ident: bib0200
  article-title: The roles of glutamate receptors across major neurological and psychiatric disorders
  publication-title: Pharmacology Biochemistry and Behavior
  contributor:
    fullname: Sanacora
– volume: 75
  start-page: 298
  year: 2015
  end-page: 305
  ident: bib0105
  article-title: Characterization: antioxidant and immunomodulatory activities of polysaccharides from
  publication-title: International Journal of Biological Macromolecules
  contributor:
    fullname: You
– volume: 75
  start-page: 465
  year: 2004
  end-page: 472
  ident: bib0255
  article-title: Isolation and biological properties of polysaccharide CPS-1 from cultured
  publication-title: Fitoterapia
  contributor:
    fullname: Zhang
– volume: 216
  start-page: 473
  year: 1995
  end-page: 482
  ident: bib0015
  article-title: 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro
  publication-title: Biochemical and Biophysical Research Communication
  contributor:
    fullname: Holsboer
– volume: 153
  start-page: 789
  year: 2008
  end-page: 795
  ident: bib0230
  article-title: Repeated administration of imipramine attenuates glutamatergic transmission in rat frontal cortex
  publication-title: Neuroscience
  contributor:
    fullname: Hess
– volume: 16
  start-page: 1953
  year: 1996
  end-page: 1957
  ident: bib0020
  article-title: The hypocholesterolemic effect of extracellular polysaccharide from the submerged fermentation of mushroom
  publication-title: Nutrition Research
  contributor:
    fullname: Cheung
– volume: 124
  start-page: 61
  year: 2009
  end-page: 68
  ident: bib0025
  article-title: Cordysinocan, a polysaccharide isolated from cultured Cordyceps: activates immune responses in cultured T-lymphocytes and macrophages: signaling cascade and induction of cytokines
  publication-title: Journal of Ethnopharmacology
  contributor:
    fullname: Bi
– volume: 156
  start-page: 3418
  year: 1996
  end-page: 3425
  ident: bib0140
  article-title: Receptor binding and internalization of a water-soluble (1→3)-beta-
  publication-title: Journal of Immunology
  contributor:
    fullname: Kelley
– volume: 14
  start-page: 847
  year: 2011
  end-page: 856
  ident: bib0085
  article-title: Phenotypic and functional maturation of dendritic cells induced by polysaccharide isolated from
  publication-title: Journal of Medicinal Food
  contributor:
    fullname: Kim
– volume: 9
  start-page: e87578
  year: 2014
  ident: bib0180
  article-title: Optimization of the solid-state fermentation and properties of a polysaccharide from
  publication-title: PLosOne
  contributor:
    fullname: Chang
– volume: 37
  start-page: 227
  year: 2000
  end-page: 236
  ident: bib0165
  article-title: Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca
  publication-title: Neuroscience Research
  contributor:
    fullname: Oliveira
– volume: 7
  start-page: 65
  year: 2009
  end-page: 74
  ident: bib0240
  article-title: Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options
  publication-title: Current Neuropharmacology
  contributor:
    fullname: Mahajan
– volume: 2
  start-page: 27
  year: 2002
  end-page: 47
  ident: bib0135
  article-title: Developmental and activity dependent regulation of ionotropic glutamate receptors at synapses
  publication-title: The Scientific World Journal
  contributor:
    fullname: Saac
– volume: 61
  start-page: 125
  year: 2005
  end-page: 131
  ident: bib0275
  article-title: Structural features and immunological activity of a polysaccharide from
  publication-title: Carbohydrate Polymers
  contributor:
    fullname: Chen
– volume: 41
  start-page: 15635
  year: 2002
  end-page: 15643
  ident: bib0070
  article-title: Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate
  publication-title: Biochemistry
  contributor:
    fullname: Gouaux
– volume: 64
  start-page: 18
  year: 2014
  end-page: 23
  ident: bib0060
  article-title: Antioxidant action of 7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cytotoxicity
  publication-title: Neurochemistry International
  contributor:
    fullname: Yao
– volume: 134
  start-page: 74
  year: 2011
  end-page: 81
  ident: bib0075
  article-title: Yokukansan, a kampo medicine: protects against glutamate cytotoxicity due to oxidative stress in PC12 cells
  publication-title: Journal of Ethnopharmacology
  contributor:
    fullname: Kase
– volume: 78
  start-page: 117
  year: 2009
  end-page: 124
  ident: bib0210
  article-title: Isolation: chemical characteristics and antioxidant properties of the polysaccharides from marine fungus
  publication-title: Carbohydrate Polymers
  contributor:
    fullname: Qi
– volume: 51
  start-page: 1140
  year: 2012
  end-page: 1146
  ident: bib0265
  article-title: Antioxidant and hepatoprotective potential of endo-polysaccharides from
  publication-title: International Journal Biological Macromolecules
  contributor:
    fullname: Fan
– volume: 28
  start-page: 2029
  year: 2012
  end-page: 2038
  ident: bib0250
  article-title: Comparison of the structural characterization and biological activity of acidic polysaccharides from
  publication-title: World Journal of Microbiology and Biotechnology
  contributor:
    fullname: Guo
– volume: 26
  start-page: 8
  year: 2010
  end-page: 16
  ident: bib0215
  article-title: Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage
  publication-title: Neuroscience Bulletin
  contributor:
    fullname: Mei
– volume: 470
  start-page: 375
  year: 2016
  end-page: 383
  ident: bib0035
  article-title: Neuroprotective effect of sulfated polysaccharide isolated from sea cucumber
  publication-title: Biochemical and Biophysical Research Communications
  contributor:
    fullname: Ji
– volume: 97
  start-page: 1634
  year: 2006
  end-page: 1658
  ident: bib0055
  article-title: Oxidative stress and neurodegeneration: where are we now?
  publication-title: Journal of Neurochemistry
  contributor:
    fullname: Halliwell
– volume: 12
  start-page: 1881
  year: 1992
  end-page: 1895
  ident: bib0170
  article-title: Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
  publication-title: Journal of Neuroscience
  contributor:
    fullname: Thayer
– volume: 904
  start-page: 395
  year: 2012
  end-page: 405
  ident: bib0050
  article-title: Antinociceptive and anti-inflammatory effects of electroacupuncture on experimental arthritis of the rat temporomandibular joint
  publication-title: Canadian Journal of Physiology and Pharmacology
  contributor:
    fullname: Vale
– volume: 9
  start-page: 373
  year: 2010
  end-page: 382
  ident: bib0005
  article-title: Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target
  publication-title: CNS & Neurological Disorders—Drug Targets
  contributor:
    fullname: Methner
– volume: 22
  start-page: 93
  year: 2015
  end-page: 100
  ident: bib0065
  article-title: Purification: characterization and neuroprotective effects of a polysaccharide from
  publication-title: Carbohydrate Polymers
  contributor:
    fullname: Lei
– volume: 50
  start-page: 3405
  year: 2002
  end-page: 3411
  ident: bib0030
  article-title: Fourier transform infrared spectroscopy and chemometric analysis of white wine polysaccharide extracts
  publication-title: Journal of Agriculture and Food Chemistry
  contributor:
    fullname: Delgadillo
– volume: 66
  start-page: 1113
  year: 2004
  end-page: 1122
  ident: bib0010
  article-title: An investigation of the neuroprotective effects of tetracycline derivatives in experimental models of retinal cell death
  publication-title: Molecular Pharmacology
  contributor:
    fullname: Kelly
– volume: 69
  start-page: 171
  year: 2014
  end-page: 175
  ident: bib0040
  article-title: Protective effects of
  publication-title: International Journal of Biological Macromolecules
  contributor:
    fullname: Yang
– volume: 25
  start-page: 675
  year: 2011
  end-page: 680
  ident: bib0195
  article-title: Protective effect of a polysaccharide isolated from a cultivated Cordyceps mycelia on hydrogen peroxide-induced oxidative damage in PC12 cells
  publication-title: Phytotherapy Research
  contributor:
    fullname: Zhang
– volume: 95
  start-page: 9
  year: 2013
  end-page: 15
  ident: bib0270
  article-title: The antioxidant activities and neuroprotective effect of polysaccharides from the starfish
  publication-title: Carbohydrate Polymers
  contributor:
    fullname: Zhang
– volume: 73
  start-page: 2503
  year: 2003
  end-page: 2513
  ident: bib0115
  article-title: A polysaccharide isolated from
  publication-title: Life Sciences
  contributor:
    fullname: Cheung
– volume: 84
  start-page: 1199
  year: 2002
  end-page: 1205
  ident: bib0150
  article-title: Lipid peroxidation-mediated cytotoxicity and DNA damage in U937 cells
  publication-title: Biochimie
  contributor:
    fullname: Park
– volume: 74
  start-page: 1605
  year: 2000
  end-page: 1612
  ident: bib0205
  article-title: Autoxidation and neurotoxicity of 6- hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson’s disease
  publication-title: Journal of Neurochemistry
  contributor:
    fullname: Labandeira-Garcia
– volume: 49
  start-page: 1477
  year: 2011
  end-page: 1483
  ident: bib0175
  article-title: A study of anti-cancer effects of
  publication-title: Food and Chemical Toxicology
  contributor:
    fullname: Worthington
– volume: 10
  start-page: 283
  year: 1990
  end-page: 292
  ident: bib0130
  article-title: Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations
  publication-title: Journal of Neuroscience
  contributor:
    fullname: Rothman
– volume: 23
  start-page: 147
  year: 2002
  end-page: 152
  ident: bib0235
  article-title: Glutamatergic mechanisms in different disease states: overview and therapeutic implications—an introduction
  publication-title: Amino Acids
  contributor:
    fullname: Tzschentke
– volume: 52
  start-page: 113
  year: 2013
  end-page: 120
  ident: bib0090
  article-title: Purification and determination of two novel antioxidant peptides from flounder fish (
  publication-title: Food and Chemical Toxicology
  contributor:
    fullname: Jeon
– volume: 50
  start-page: 3190
  year: 2012
  end-page: 3197
  ident: bib0080
  article-title: Activation of macrophages by polysaccharide isolated from
  publication-title: Food and Chemical Toxicology
  contributor:
    fullname: Yoon
– volume: 23
  start-page: 637
  year: 1997
  end-page: 647
  ident: bib0160
  article-title: Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress
  publication-title: Free Radical Biology Medicine
  contributor:
    fullname: Oliveira
– year: 1992
  ident: bib0225
  article-title: Chinese drugs of plant origin
  contributor:
    fullname: Eisenbrand
– volume: 724
  start-page: 31
  year: 2014
  end-page: 42
  ident: bib0145
  article-title: Rotigotine protects against glutamate toxicity in primary dopaminergic cell culture
  publication-title: European Journal of Pharmacology
  contributor:
    fullname: Reichmann
– volume: 90
  start-page: 1395
  year: 2012
  end-page: 1410
  ident: bib0280
  article-title: Anticancer polysaccharides from natural resources: a review of recent research
  publication-title: Carbohydrate Polymers
  contributor:
    fullname: Wang
– volume: 256
  start-page: 237
  year: 2002
  end-page: 248
  ident: bib0185
  article-title: Surface chemical studies on sphalerite and galena using extracellular polysaccharides isolated from
  publication-title: Journal of Colloid and Interface Science
  contributor:
    fullname: Natarajan
– volume: 73
  start-page: 2503
  year: 2003
  ident: 10.1016/j.carbpol.2016.06.108_bib0115
  article-title: A polysaccharide isolated from Cordyceps sinensis, a traditional Chinese medicine: protects PC12 cells against hydrogen peroxide-induced injury
  publication-title: Life Sciences
  doi: 10.1016/S0024-3205(03)00652-0
  contributor:
    fullname: Li
– volume: 9
  start-page: e87578
  year: 2014
  ident: 10.1016/j.carbpol.2016.06.108_bib0180
  article-title: Optimization of the solid-state fermentation and properties of a polysaccharide from Paecilomyces cicadae (Miquel) Samson and its antioxidant activities in vitro
  publication-title: PLosOne
  doi: 10.1371/journal.pone.0087578
  contributor:
    fullname: Ren
– volume: 904
  start-page: 395
  year: 2012
  ident: 10.1016/j.carbpol.2016.06.108_bib0050
  article-title: Antinociceptive and anti-inflammatory effects of electroacupuncture on experimental arthritis of the rat temporomandibular joint
  publication-title: Canadian Journal of Physiology and Pharmacology
  doi: 10.1139/y2012-003
  contributor:
    fullname: Gondim
– volume: 21
  start-page: 7455
  year: 2001
  ident: 10.1016/j.carbpol.2016.06.108_bib0190
  article-title: Oxidative glutamate toxicity can be a component of the excitotoxicity cascade
  publication-title: Journal of Neuroscience
  doi: 10.1523/JNEUROSCI.21-19-07455.2001
  contributor:
    fullname: Schubert
– volume: 12
  start-page: 1881
  year: 1992
  ident: 10.1016/j.carbpol.2016.06.108_bib0170
  article-title: Glutamate-induced calcium transient triggers delayed calcium overload and neurotoxicity in rat hippocampal neurons
  publication-title: Journal of Neuroscience
  doi: 10.1523/JNEUROSCI.12-05-01882.1992
  contributor:
    fullname: Randall
– volume: 41
  start-page: 15635
  year: 2002
  ident: 10.1016/j.carbpol.2016.06.108_bib0070
  article-title: Mechanism of activation and selectivity in a ligand-gated ion channel: structural and functional studies of GluR2 and quisqualate
  publication-title: Biochemistry
  doi: 10.1021/bi020583k
  contributor:
    fullname: Jin
– volume: 25
  start-page: 675
  year: 2011
  ident: 10.1016/j.carbpol.2016.06.108_bib0195
  article-title: Protective effect of a polysaccharide isolated from a cultivated Cordyceps mycelia on hydrogen peroxide-induced oxidative damage in PC12 cells
  publication-title: Phytotherapy Research
  doi: 10.1002/ptr.3320
  contributor:
    fullname: Shen
– volume: 26
  start-page: 8
  year: 2010
  ident: 10.1016/j.carbpol.2016.06.108_bib0215
  article-title: Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage
  publication-title: Neuroscience Bulletin
  doi: 10.1007/s12264-010-0813-7
  contributor:
    fullname: Sun
– volume: 470
  start-page: 375
  year: 2016
  ident: 10.1016/j.carbpol.2016.06.108_bib0035
  article-title: Neuroprotective effect of sulfated polysaccharide isolated from sea cucumber Stichopus japonicus on 6-OHDA-induced death in SH-SY5Y through inhibition of MAPK and NF-(B and activation of PI3 K/Akt signaling pathways
  publication-title: Biochemical and Biophysical Research Communications
  doi: 10.1016/j.bbrc.2016.01.035
  contributor:
    fullname: Cui
– volume: 14
  start-page: 847
  year: 2011
  ident: 10.1016/j.carbpol.2016.06.108_bib0085
  article-title: Phenotypic and functional maturation of dendritic cells induced by polysaccharide isolated from Paecilomyces cicadae
  publication-title: Journal of Medicinal Food
  doi: 10.1089/jmf.2011.1575
  contributor:
    fullname: Kim
– volume: 22
  start-page: 1737
  year: 2002
  ident: 10.1016/j.carbpol.2016.06.108_bib0045
  article-title: Anticancer effects and mechanism of polysaccharide-K (PSK): implications of cancer immunotherapy
  publication-title: Anticancer Research
  contributor:
    fullname: Fisher
– volume: 724
  start-page: 31
  year: 2014
  ident: 10.1016/j.carbpol.2016.06.108_bib0145
  article-title: Rotigotine protects against glutamate toxicity in primary dopaminergic cell culture
  publication-title: European Journal of Pharmacology
  doi: 10.1016/j.ejphar.2013.12.014
  contributor:
    fullname: Oster
– volume: 23
  start-page: 637
  year: 1997
  ident: 10.1016/j.carbpol.2016.06.108_bib0160
  article-title: Glutamate toxicity on a PC12 cell line involves glutathione (GSH) depletion and oxidative stress
  publication-title: Free Radical Biology Medicine
  doi: 10.1016/S0891-5849(97)00020-8
  contributor:
    fullname: Pereira
– volume: 61
  start-page: 125
  year: 2005
  ident: 10.1016/j.carbpol.2016.06.108_bib0275
  article-title: Structural features and immunological activity of a polysaccharide from Dioscorea opposita Thunb roots
  publication-title: Carbohydrate Polymers
  doi: 10.1016/j.carbpol.2005.04.020
  contributor:
    fullname: Zhao
– volume: 156
  start-page: 3418
  year: 1996
  ident: 10.1016/j.carbpol.2016.06.108_bib0140
  article-title: Receptor binding and internalization of a water-soluble (1→3)-beta-d-glucan biologic response modifier in two monocyte/macrophage cell lines
  publication-title: Journal of Immunology
  doi: 10.4049/jimmunol.156.9.3418
  contributor:
    fullname: Muller
– volume: 256
  start-page: 237
  year: 2002
  ident: 10.1016/j.carbpol.2016.06.108_bib0185
  article-title: Surface chemical studies on sphalerite and galena using extracellular polysaccharides isolated from Bacillus polymyxa
  publication-title: Journal of Colloid and Interface Science
  doi: 10.1006/jcis.2002.8681
  contributor:
    fullname: Santhiya
– volume: 52
  start-page: 113
  year: 2013
  ident: 10.1016/j.carbpol.2016.06.108_bib0090
  article-title: Purification and determination of two novel antioxidant peptides from flounder fish (Paralichthys olivaceus) using digestive proteases
  publication-title: Food and Chemical Toxicology
  doi: 10.1016/j.fct.2012.10.058
  contributor:
    fullname: Ko
– volume: 50
  start-page: 3405
  year: 2002
  ident: 10.1016/j.carbpol.2016.06.108_bib0030
  article-title: Fourier transform infrared spectroscopy and chemometric analysis of white wine polysaccharide extracts
  publication-title: Journal of Agriculture and Food Chemistry
  doi: 10.1021/jf020074p
  contributor:
    fullname: Coimbra
– volume: 50
  start-page: 3190
  year: 2012
  ident: 10.1016/j.carbpol.2016.06.108_bib0080
  article-title: Activation of macrophages by polysaccharide isolated from Paecilomyces cicadae through toll-like receptor 4
  publication-title: Food and Chemical Toxicology
  doi: 10.1016/j.fct.2012.05.051
  contributor:
    fullname: Kim
– volume: 50
  start-page: 2294
  year: 2012
  ident: 10.1016/j.carbpol.2016.06.108_bib0095
  article-title: Protective effect of a novel antioxidant peptide purified from a marine Chlorella elthpsoidea protein against free radical-induced oxidative stress
  publication-title: Food and Chemical Toxicology
  doi: 10.1016/j.fct.2012.04.022
  contributor:
    fullname: Ko
– volume: 10
  start-page: 283
  year: 1990
  ident: 10.1016/j.carbpol.2016.06.108_bib0130
  article-title: Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations
  publication-title: Journal of Neuroscience
  doi: 10.1523/JNEUROSCI.10-01-00283.1990
  contributor:
    fullname: Michaels
– volume: 100
  start-page: 653
  year: 2012
  ident: 10.1016/j.carbpol.2016.06.108_bib0200
  article-title: The roles of glutamate receptors across major neurological and psychiatric disorders
  publication-title: Pharmacology Biochemistry and Behavior
  doi: 10.1016/j.pbb.2011.11.002
  contributor:
    fullname: Siegel
– volume: 153
  start-page: 789
  year: 2008
  ident: 10.1016/j.carbpol.2016.06.108_bib0230
  article-title: Repeated administration of imipramine attenuates glutamatergic transmission in rat frontal cortex
  publication-title: Neuroscience
  doi: 10.1016/j.neuroscience.2008.03.007
  contributor:
    fullname: Tokarski
– volume: 22
  start-page: 93
  year: 2015
  ident: 10.1016/j.carbpol.2016.06.108_bib0065
  article-title: Purification: characterization and neuroprotective effects of a polysaccharide from Gynostemma pentaphyllum
  publication-title: Carbohydrate Polymers
  doi: 10.1016/j.carbpol.2014.12.032
  contributor:
    fullname: Jia
– volume: 78
  start-page: 117
  year: 2009
  ident: 10.1016/j.carbpol.2016.06.108_bib0210
  article-title: Isolation: chemical characteristics and antioxidant properties of the polysaccharides from marine fungus Penicillium sp. F23-2
  publication-title: Carbohydrate Polymers
  doi: 10.1016/j.carbpol.2009.04.017
  contributor:
    fullname: Sun
– volume: 51
  start-page: 1140
  year: 2012
  ident: 10.1016/j.carbpol.2016.06.108_bib0265
  article-title: Antioxidant and hepatoprotective potential of endo-polysaccharides from Hericium erinaceus grown on tofu whey
  publication-title: International Journal Biological Macromolecules
  doi: 10.1016/j.ijbiomac.2012.09.002
  contributor:
    fullname: Zhang
– volume: 31
  start-page: 531
  year: 2010
  ident: 10.1016/j.carbpol.2016.06.108_bib0220
  article-title: Parkinson’s disease: oxidative stress and therapeutic approaches
  publication-title: Neurological Sciences
  doi: 10.1007/s10072-010-0245-1
  contributor:
    fullname: Surendran
– volume: 1
  start-page: 120
  year: 2000
  ident: 10.1016/j.carbpol.2016.06.108_bib0125
  article-title: Apoptosis in neurodegenerative disorders
  publication-title: Nature Reviews Molecular Cell Biology
  doi: 10.1038/35040009
  contributor:
    fullname: Mattson
– volume: 124
  start-page: 61
  year: 2009
  ident: 10.1016/j.carbpol.2016.06.108_bib0025
  article-title: Cordysinocan, a polysaccharide isolated from cultured Cordyceps: activates immune responses in cultured T-lymphocytes and macrophages: signaling cascade and induction of cytokines
  publication-title: Journal of Ethnopharmacology
  doi: 10.1016/j.jep.2009.04.010
  contributor:
    fullname: Cheung
– volume: 216
  start-page: 473
  year: 1995
  ident: 10.1016/j.carbpol.2016.06.108_bib0015
  article-title: 17-beta estradiol protects neurons from oxidative stress-induced cell death in vitro
  publication-title: Biochemical and Biophysical Research Communication
  doi: 10.1006/bbrc.1995.2647
  contributor:
    fullname: Behl
– volume: 75
  start-page: 298
  year: 2015
  ident: 10.1016/j.carbpol.2016.06.108_bib0105
  article-title: Characterization: antioxidant and immunomodulatory activities of polysaccharides from Prunella vulgaris Linn
  publication-title: International Journal of Biological Macromolecules
  doi: 10.1016/j.ijbiomac.2015.01.010
  contributor:
    fullname: Li
– volume: 37
  start-page: 227
  year: 2000
  ident: 10.1016/j.carbpol.2016.06.108_bib0165
  article-title: Oxidative glutamate toxicity involves mitochondrial dysfunction and perturbation of intracellular Ca2+ homeostasis
  publication-title: Neuroscience Research
  doi: 10.1016/S0168-0102(00)00124-3
  contributor:
    fullname: Pereira
– volume: 75
  start-page: 465
  year: 2004
  ident: 10.1016/j.carbpol.2016.06.108_bib0255
  article-title: Isolation and biological properties of polysaccharide CPS-1 from cultured Cordyceps militaris
  publication-title: Fitoterapia
  doi: 10.1016/j.fitote.2004.04.003
  contributor:
    fullname: Yu
– volume: 74
  start-page: 1605
  year: 2000
  ident: 10.1016/j.carbpol.2016.06.108_bib0205
  article-title: Autoxidation and neurotoxicity of 6- hydroxydopamine in the presence of some antioxidants: potential implication in relation to the pathogenesis of Parkinson’s disease
  publication-title: Journal of Neurochemistry
  doi: 10.1046/j.1471-4159.2000.0741605.x
  contributor:
    fullname: Soto-Otero
– volume: 90
  start-page: 1395
  year: 2012
  ident: 10.1016/j.carbpol.2016.06.108_bib0280
  article-title: Anticancer polysaccharides from natural resources: a review of recent research
  publication-title: Carbohydrate Polymers
  doi: 10.1016/j.carbpol.2012.07.026
  contributor:
    fullname: Zong
– volume: 16
  start-page: 1953
  year: 1996
  ident: 10.1016/j.carbpol.2016.06.108_bib0020
  article-title: The hypocholesterolemic effect of extracellular polysaccharide from the submerged fermentation of mushroom
  publication-title: Nutrition Research
  doi: 10.1016/S0271-5317(96)00218-7
  contributor:
    fullname: Cheung
– volume: 66
  start-page: 1113
  year: 2004
  ident: 10.1016/j.carbpol.2016.06.108_bib0010
  article-title: An investigation of the neuroprotective effects of tetracycline derivatives in experimental models of retinal cell death
  publication-title: Molecular Pharmacology
  doi: 10.1124/mol.104.001081
  contributor:
    fullname: Baptisite
– volume: 330
  start-page: 613
  year: 1994
  ident: 10.1016/j.carbpol.2016.06.108_bib0120
  article-title: Excitatory amino acids as a final common pathway for neurologic disorders
  publication-title: New England Journal of Medicine
  doi: 10.1056/NEJM199403033300907
  contributor:
    fullname: Lipton
– volume: 28
  start-page: 2029
  year: 2012
  ident: 10.1016/j.carbpol.2016.06.108_bib0250
  article-title: Comparison of the structural characterization and biological activity of acidic polysaccharides from Cordyceps militaris cultured with different media
  publication-title: World Journal of Microbiology and Biotechnology
  doi: 10.1007/s11274-012-1005-6
  contributor:
    fullname: Wu
– volume: 49
  start-page: 1477
  year: 2011
  ident: 10.1016/j.carbpol.2016.06.108_bib0175
  article-title: A study of anti-cancer effects of Funalia trogii in vitro and in vivo
  publication-title: Food and Chemical Toxicology
  doi: 10.1016/j.fct.2011.02.008
  contributor:
    fullname: Rashid
– volume: 7
  start-page: 65
  year: 2009
  ident: 10.1016/j.carbpol.2016.06.108_bib0240
  article-title: Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options
  publication-title: Current Neuropharmacology
  doi: 10.2174/157015909787602823
  contributor:
    fullname: Uttara
– volume: 97
  start-page: 1634
  year: 2006
  ident: 10.1016/j.carbpol.2016.06.108_bib0055
  article-title: Oxidative stress and neurodegeneration: where are we now?
  publication-title: Journal of Neurochemistry
  doi: 10.1111/j.1471-4159.2006.03907.x
  contributor:
    fullname: Halliwell
– volume: 64
  start-page: 18
  year: 2014
  ident: 10.1016/j.carbpol.2016.06.108_bib0060
  article-title: Antioxidant action of 7,8-dihydroxyflavone protects PC12 cells against 6-hydroxydopamine-induced cytotoxicity
  publication-title: Neurochemistry International
  doi: 10.1016/j.neuint.2013.10.018
  contributor:
    fullname: Han
– volume: 2
  start-page: 27
  year: 2002
  ident: 10.1016/j.carbpol.2016.06.108_bib0135
  article-title: Developmental and activity dependent regulation of ionotropic glutamate receptors at synapses
  publication-title: The Scientific World Journal
  doi: 10.1100/tsw.2002.74
  contributor:
    fullname: Molnar
– volume: 69
  start-page: 171
  year: 2014
  ident: 10.1016/j.carbpol.2016.06.108_bib0040
  article-title: Protective effects of Gynostemma pentaphyllum polysaccharides on PC12 cells impaired by MPP+
  publication-title: International Journal of Biological Macromolecules
  doi: 10.1016/j.ijbiomac.2014.05.049
  contributor:
    fullname: Deng
– volume: 56
  start-page: 569
  year: 2010
  ident: 10.1016/j.carbpol.2016.06.108_bib0245
  article-title: A non-muscle myosin II motor links NR1 to retrograde trafficking and proteasomal degradation in PC12 cells
  publication-title: Neurochemistry International
  doi: 10.1016/j.neuint.2009.12.020
  contributor:
    fullname: Vazhappilly
– volume: 13
  start-page: 209
  year: 2002
  ident: 10.1016/j.carbpol.2016.06.108_bib0100
  article-title: Cyclodepsipeptide and dioxomorpholine derivatives isolated from the insect-body portion of the fungus Cordyceps cicadae
  publication-title: Journal of Chinese Medicine
  contributor:
    fullname: Kuo
– year: 1992
  ident: 10.1016/j.carbpol.2016.06.108_bib0225
  contributor:
    fullname: Tang
– volume: 9
  start-page: 373
  year: 2010
  ident: 10.1016/j.carbpol.2016.06.108_bib0005
  article-title: Mechanisms of oxidative glutamate toxicity: the glutamate/cystine antiporter system xc- as a neuroprotective drug target
  publication-title: CNS & Neurological Disorders—Drug Targets
  doi: 10.2174/187152710791292567
  contributor:
    fullname: Albrecht
– volume: 23
  start-page: 147
  year: 2002
  ident: 10.1016/j.carbpol.2016.06.108_bib0235
  article-title: Glutamatergic mechanisms in different disease states: overview and therapeutic implications—an introduction
  publication-title: Amino Acids
  doi: 10.1007/s00726-001-0120-8
  contributor:
    fullname: Tzschentke
– volume: 95
  start-page: 9
  year: 2013
  ident: 10.1016/j.carbpol.2016.06.108_bib0270
  article-title: The antioxidant activities and neuroprotective effect of polysaccharides from the starfish Asterias rollestoni
  publication-title: Carbohydrate Polymers
  doi: 10.1016/j.carbpol.2013.02.035
  contributor:
    fullname: Zhang
– volume: 1056
  start-page: 132
  year: 2005
  ident: 10.1016/j.carbpol.2016.06.108_bib0155
  article-title: Effects of N-acetylcysteine amide (NACA), a novel thiol antioxidant against glutamate-induced cytotoxicity in neuronal cell line PC12
  publication-title: Brain Research
  doi: 10.1016/j.brainres.2005.07.032
  contributor:
    fullname: Penugonda
– volume: 134
  start-page: 74
  year: 2011
  ident: 10.1016/j.carbpol.2016.06.108_bib0075
  article-title: Yokukansan, a kampo medicine: protects against glutamate cytotoxicity due to oxidative stress in PC12 cells
  publication-title: Journal of Ethnopharmacology
  doi: 10.1016/j.jep.2010.11.063
  contributor:
    fullname: Kawakami
– volume: 111
  start-page: 458
  year: 2007
  ident: 10.1016/j.carbpol.2016.06.108_bib0110
  article-title: Protective effects of ginsenoside Rg2 against glutamate-induced neurotoxicity in PC12 cells
  publication-title: Journal of Ethnopharmacology
  doi: 10.1016/j.jep.2006.12.015
  contributor:
    fullname: Li
– volume: 18
  start-page: 4
  year: 2007
  ident: 10.1016/j.carbpol.2016.06.108_bib0260
  article-title: Antitumor polysaccharides from mushrooms: a review on their isolation process: structural characteristics and antitumor activity
  publication-title: Trends in Food Science & Technology
  doi: 10.1016/j.tifs.2006.07.013
  contributor:
    fullname: Zhang
– volume: 84
  start-page: 1199
  year: 2002
  ident: 10.1016/j.carbpol.2016.06.108_bib0150
  article-title: Lipid peroxidation-mediated cytotoxicity and DNA damage in U937 cells
  publication-title: Biochimie
  doi: 10.1016/S0300-9084(02)00039-1
  contributor:
    fullname: Park
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Snippet •Two polysaccharides CPA-1 and CPB-2 were purified from Cordyceps cicadae.•CPA-1 and CPB-2 protected PC12 cells from glutamate induced toxicity by increasing...
Two polysaccharides CPA-1 and CPB-2 were isolated purified from Cordyceps cicadae by hot water extraction, ethanol precipitation and purification using anion...
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elsevier
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StartPage 187
SubjectTerms Cordyceps cicadae
Glutamate
Neuroprotection
PC12 cells
Polysaccharide
Title Polysaccharides purified from Cordyceps cicadae protects PC12 cells against glutamate-induced oxidative damage
URI https://dx.doi.org/10.1016/j.carbpol.2016.06.108
https://www.ncbi.nlm.nih.gov/pubmed/27561486
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