An Immunohistochemical Study of the Organization of Ganglia and Nerve Fibres in the Mucosa of the Porcine Intestine
Summary In order to elucidate the organization of the enteric nervous system in the mucous plexus, wholemounts from six intestinal regions in six pigs were studied by vasoactive intestinal peptide, substance P, nitric oxide synthase and neurofilament proteins immunohistochemistry. The mucous plexus...
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Published in | Anatomia, histologia, embryologia Vol. 31; no. 4; pp. 237 - 246 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Berlin, Germany
Blackwell Verlag GmbH
01.08.2002
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Subjects | |
Online Access | Get full text |
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Summary: | Summary
In order to elucidate the organization of the enteric nervous system in the mucous plexus, wholemounts from six intestinal regions in six pigs were studied by vasoactive intestinal peptide, substance P, nitric oxide synthase and neurofilament proteins immunohistochemistry. The mucous plexus of both large and small intestine contained ganglia and isolated neurons. They were many and comparably larger in the caecum and colon, few in the ileum, and fewer and smaller in the jejunum. The mucous plexus was subdivided into the lamina muscularis mucosae and lamina proprial subplexuses, and based on location the latter was subdivided further in order to clarify their variations with respect to the amount, sizes and shapes of ganglia and neurons, sizes and orientation of nerve strands and immunoreactivities. Ganglia were situated at different topographical levels in the lamina muscularis mucosae subplexus, outer proprial and interglandular proprial meshworks in the lamina proprial subplexus with the majority of ganglia occurring in the outer proprial meshwork. The mucous plexus in the intestine of the pig is thus a ganglionated plexus showing marked segmental variation in the amount of intramucosal ganglia and isolated nerve cells. These new observations, calls for a re‐examination of the mucous plexus to elucidate the regulatory mechanisms of importance in mucosal functions and consideration of the mucous plexus in the intestine of the pig to be one of the major ganglionated plexuses. |
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Bibliography: | ArticleID:403 ark:/67375/WNG-G6D2TB92-0 istex:450F372554937C5D59E75357AFCAEA2D78272966 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 0340-2096 1439-0264 |
DOI: | 10.1046/j.1439-0264.2002.00403.x |