A case of marked ST depression and myocardial injury as a result of disulfiram–ethanol reaction

Summary We report a case of a 50-year-old man with intractable hypotension, which led to ischemic electrocardiogram (ECG) changes and myocardial injury due to relative myocardial ischemia as a result of a disulfiram–ethanol reaction. This is the first report that assessed cardiac function during hyp...

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Published inJournal of cardiology cases Vol. 1; no. 3; pp. e137 - e140
Main Authors Shioji, Keisuke, MD, PhD, Izuhara, Masayasu, MD, Kadota, Shin, MD, Baba, Osamu, MD, Mitsuoka, Hirokazu, MD, PhD, Uegaito, Takashi, MD, PhD, Matsuda, Mitsuo, MD, PhD, FJCC
Format Journal Article
LanguageEnglish
Published Japan Japanese College of Cardiology 01.06.2010
Subjects
Cardiovascular
Shock
Electrocardiography
Angiocardiography
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Summary:Summary We report a case of a 50-year-old man with intractable hypotension, which led to ischemic electrocardiogram (ECG) changes and myocardial injury due to relative myocardial ischemia as a result of a disulfiram–ethanol reaction. This is the first report that assessed cardiac function during hypotension and ischemic ECG changes by emergency coronary angiography, left ventriculography, and right heart catheterization. This case indicates that disulfiram potentially has fatal side effects due to a disulfiram–ethanol reaction.
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ISSN:1878-5409
1878-5409
DOI:10.1016/j.jccase.2009.11.002