The chemistry and biology of organic guanidine derivatives

Covering: 2010 and 2011. Previous review: Nat. Prod. Rep. , 2010, 27 , 1871 The chemistry and biology of organic natural guanidines are reviewed, including the isolation, structure determination, synthesis, biosynthesis and biological activities of alkaloids, non-ribosomal peptides, guanidine-bearin...

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Published inNatural product reports Vol. 29; no. 12; pp. 1382 - 146
Main Authors Berlinck, Roberto G. S, Trindade-Silva, Amaro E, Santos, Mario F. C
Format Journal Article
LanguageEnglish
Published England 01.01.2012
Subjects
Animals
Bacteria - chemistry
Biological Products - chemistry
Biological Products - isolation & purification
Biological Products - pharmacology
Guanidines - chemistry
Guanidines - isolation & purification
Guanidines - pharmacology
Invertebrates - chemistry
Molecular Structure
Plants, Medicinal - chemistry
Polyketides - chemistry
Polyketides - isolation & purification
Polyketides - pharmacology
Terpenes - chemistry
Terpenes - isolation & purification
Terpenes - pharmacology
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Summary:Covering: 2010 and 2011. Previous review: Nat. Prod. Rep. , 2010, 27 , 1871 The chemistry and biology of organic natural guanidines are reviewed, including the isolation, structure determination, synthesis, biosynthesis and biological activities of alkaloids, non-ribosomal peptides, guanidine-bearing terpenes, polyketides and shikimic acid derivatives from natural sources. The chemistry and biology of organic natural guanidines are reviewed, including the isolation, structure determination, synthesis, biosynthesis and biological activities of alkaloids, non-ribosomal peptides, guanidine-bearing terpenes, polyketides and shikimic acid derivatives from natural sources.
Bibliography:Amaro E. Trindade Silva graduated in Microbiology and Immunology (2000), and obtained his MSc (2002) and PhD (2009) degrees in Genetics, at the Universidade Federal do Rio de Janeiro (UFRJ). His PhD was partially developed at the group of Prof. Margo Haygood (OHSU). Since 2009 his has been a post-doctoral fellow at the Instituto de Quimica de Sao Carlos (USP), under the supervision of Prof. Roberto G. S. Berlinck, and in collaboration with Prof. Fabiano L Thompson (Universidade Federal do Rio de Janeiro). His interest is the characterization and engineering of biosynthetic genes clusters from marine invertebrate microbiomes.
Roberto G. S. Berlinck joined the Instituto de Quimica de Sao Carlos, Universidade de Sao Paulo in 1993. He was appointed as associate professor in 2001 and as full professor in 2010. During 1997 and 1998 he spent a six month sabbatical with Professor Raymond J. Andersen (UBC). Since 1994 his research interests have been related to the isolation, identification, biological activities and biosynthesis of natural products from marine invertebrates and microorganisms.
Mario F. C. Santos graduated in chemistry (2009) and obtained his MSc. degree (2011) at the Department of Chemistry of the Universidade Federal de Sergipe. Since 2011 he has been a PhD student the Instituto de Quimica de Sao Carlos, Universidade de Sao Paulo, under the supervision of Prof. Berlinck. His interests include the chemistry and biology of secondary metabolites from marine invertebrates and microorganisms.
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ISSN:0265-0568
1460-4752
DOI:10.1039/c2np20071f