Surveillance in patients with stage I testicular nonseminomatous germ cell tumors

Fourteen patients with testicular nonseminomatous germ cell tumor, clinical stage I were entered into a surveillance study. Median age was 31 (range 18-58). Three patients had pure tumor, and 11, mixed tumor. In 2 patients, vascular invasion was noted, and in 1, involvement of the spermatic cord. Se...

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Bibliographic Details
Published inCancer investigation Vol. 11; no. 1; p. 10
Main Authors Gez, E, Wygoda, M, Nussbaum, N, Figer, A, Gil, R I, Inbal, M
Format Journal Article
LanguageEnglish
Published England 1993
Subjects
Adolescent
Adult
Follow-Up Studies
Humans
Male
Middle Aged
Neoplasm Recurrence, Local - diagnosis
Neoplasm Staging
Neoplasms, Germ Cell and Embryonal - pathology
Neoplasms, Germ Cell and Embryonal - surgery
Neoplasms, Germ Cell and Embryonal - therapy
Orchiectomy
Prospective Studies
Testicular Neoplasms - pathology
Testicular Neoplasms - surgery
Testicular Neoplasms - therapy
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Summary:Fourteen patients with testicular nonseminomatous germ cell tumor, clinical stage I were entered into a surveillance study. Median age was 31 (range 18-58). Three patients had pure tumor, and 11, mixed tumor. In 2 patients, vascular invasion was noted, and in 1, involvement of the spermatic cord. Serum alpha fetoprotein and beta subunit choriogonadotropin were high in 9 and in 3 patients, respectively. In median follow-up of 21 months (range 2-63), 3 patients relapsed: 1 had inguinal lymphadenopathy and 2 had lung metastases at 12, 4, and 16 months, respectively. Salvage chemotherapy PEB and PVB achieved complete response in the latter 2 patients for 6 and 49 months. Except for 1 patient lost to follow-up, all are alive.
ISSN:0735-7907
DOI:10.3109/07357909309020255