Silk fibroin/methacrylated gelatine/hydroxyapatite biomimetic nanofibrous membranes for guided bone regeneration

• Published in: International journal of biological macromolecules Vol. 263; no. Pt 2; p. 130380
• Main Authors: Li, Bo, Chen, Ying, He, Jisu, Shu, Yue, Yang, Haocheng, Liu, Junhong, Zhang, Chi, Xiao, Wenqian, Liu, Zhongning, Liao, Xiaoling
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.04.2024
• Subjects: animal models; biocompatibility; biomimetics; bone formation; Bone regeneration; fibroins; gelatin; hydroxyapatite; Methacrylated gelatine; nanofibers; Silk fibroin; Bone regeneration; Silk fibroin; Methacrylated gelatine

By mimicking in vivo bionic microenvironment and promoting osteogenic differentiation, the hybrid organic-inorganic nanofibrous membranes provide promising potential for guided bone regeneration (GBR) in the treatment of clinical bone defects. To develop a degradable and osteogenic membrane for GBR...